Ciclesonide Nasal Spray for Allergic Rhinitis
Omnaris (ciclesonide) iine nasal steroid iyo ichangobva kuwanika pakurapa kwemaviri. Omnaris anosangana nemamwe akawanda e nasal steroid inowanika kurapwa kweergenic rhinitis , kusanganisira Flonase (fluticasone propionate), Nasonex (mometasone), Veramyst (fluticasone furoate), Rhinocort (budesonide), Nasacort (triamcinolone) nezvimwe.
Iwe unogona kunge uchishamisika, nezvose izvi zvinodhaka, tinoda imwezve steroid yemasal? Mune maonero angu, steroid chero ipi zvayo inoda kutanga niche inoparadzanisa kubva kune imwe yose yepakiti.
Maitiro Omunari Akasiyana Sei?
Omnaris is pro-drug that is metabolized to its form in the nasal mucosa. Izvi zvinoreva kuti inopihwa kumhino mumhando isina kushanda, uye yakashandurwa kuva mushonga unoshandiswa nemaine enzymes mukati memhino. Isati yasimbiswa nema-enzymes aya, haina zvishoma kune steroid miitiro yakasati yatanga kushanda mukati memhino. Nokudaro, Omnaris haazivikanwe zvizere-muviri steroid zvinokonzera , kusanganisira hapana kuwedzera kungozi ye glaucoma, chirongwa checataract, kana Cushing's syndrome.
Omnaris anouyawo mune imwe hypotonic solution (yakaderera mumumvuri yakasviba iyo iri muropa revanhu), iyo inochengetedza mishonga mumhino refu, uye haikwanisi kubuda mumutsipa. Kusiyana nedzimwe steroid dzakawanda, hadzina benzalkonium chloride sekuchengetedza.
Izvi zvinodzivirirwa zvinozivikanwa kuti zvinokonzera migumisiro mukati memhuno, zvakadai sokuderera kwekutakura kwekuyananisa mukati memhuno (iyo ye "mutezo-kuchenesa" inoputika), kutsamwiswa kwekamuri yemhino, uye kuderedza kushanda kwehutachiona-kurwisana masero machena eropa mukati memhino. Panzvimbo ye benzalkonium chloride, Omnaris ine potassium sorbate sekuchengetedza.
Omnaris Still Has Some Side Effects
Asi usanyengerwa - Wemunisitiri achiri nemigumisiro yechirwere, yakanyanya kuve kuvhara mumuromo, kusuruvara kwemhino nehuro, uyewo musoro. Zvisinei, izvi zvisingabatsiri zvakanga zvisina kunyanya kuwirirana neOnnaris kana zvichienzaniswa ne placebo (mishonga yakaipa) mune zvidzidzo zvakasiyana-siyana.
Ko Omnaris angave ari nani here steroid yeanal kupfuura vamwe vatove pamusika? Nguva ichataura. Munguva iyi, nasal steroids inomirira mushonga mumwe chete wakanakisisa wokurapa chirwere chinonzi allergenic rhinitis .
Sources:
> Ratner PH, Wingertzahn MA, van Bazel JH, Hampel F, Darken PF, Shah T. Efficacy uye kuchengetedzwa kweCiclesonide Nasal Spray nokuda kweTraining of Seasonal Allergic Rhinitis. J Allergy Clin Immunol. 2006; 118: 1142-8.
> Meltzer EO, Kunjibettu S, Hall N, Wingertzahn MA, Murcia C, Berger W, LaForce C. Efficacy uye Kuchengetedzwa kweCiclesonide, 200 mcg Kamwe Chero Nezuva, pakurapa kwekusingaperi kweAirgic Rhinitis. Ann Allergy Chirwere Immunol. 2007; 98: 175-181.
> Chervinsky P, Kunjibettu S, Miller DL, > Prenner > BM, Raphael G, Hall M, Shah T. Kuchengetedza kwenguva refu > uye > Kubudirira kweIntranasal Ciclesonide muVanhu Vakura uye Vachiri Kuyaruka Varwere Vanorarama Perennial Allergic Rhinitis. Ann Allergy Chirwere Immunol. 2007; 99: 69-76.