Makomborero Angave Akazvininipisa, Kuchenjerera Kunofanira Kutorwa Mune Mimwe Mhosva
Imishonga inodhaka yemishonga trazodone inowanzopiwa yakagadziriswa antidipressant iyo inoshandiswawo kunze kwe-label sekufungidzira kuti utange kurara. Yakashandiswa kwemakumi emakore semubatsiro wehope, asi trazodone inoshanda sei? Inoshanda zvakadini pamwero wepamusoro kuvandudza kugona hope kana kurara zvimwe usiku? Ndezvipi zvinowanzova nemigumisiro? Dzidza kana trazodone yakakosha iwe uye zvimwe zvipi zvingave zvakakosha kufunga, kusanganisira kudiwa kwehope yekurara kana chirwere chisingaperi chisingaiti.
Zvishandiso
Trazodone mishonga yakwegura yakashandiswa kurapa kuora mwoyo uye kushushikana kwakanyanya kwemakore mazhinji. Sezvo inenge ichiita zvekunyengedza kana kugadzirisa migumisiro, zvichireva kuti inokonzera kugona, zvinobatsirawo pakurapa kusuruvara kana kushaya njodzi .
Chinoshanda sei?
Hazvizivikanwi zvakajeka kuti trazodone inoshanda sei. Chinozivikanwa ndechokuti chinoshanda pamagetsi eurotransmitters, ayo ari makemikari vatumwa mukati meuropi. Iyo inobvumira neurotransmitter inonzi serotonin inovaka mukati memiganhu pakati pemasero emagetsi nekudzivirira kubata kwayo mumasero ari pedyo. Inoratidzikawo kuti inopindirana ne histamine (uye antihistamine sezinonzi diphenhydramine inonyatsozivikanwa sevashandi vekurara). Izvi zvinoratidzika sezvibatana zvinowedzera kunono-wave (kana N3) kurara.
IAmerican Academy yeSleep Medicine haisi kukurudzira ikozvino kushandiswa kwetrazodone kurwara kusuruvara, zvichiratidza kuti mungozi dzingangodaro uye zvinokuvadza zvinopfuura zvikomborero.
Izvi zvinovakirwa pakutsvakurudza kunoratidza kuti nguva inotora kurara inongopedzisira ichingoderedzwa kuburikidza nevhareji yemaminitsi gumi nekushandiswa kwetrazodone kuenzaniswa ne placebo. Mukuwedzera, nguva yakawanda inopedzisira yakamuka usiku inongopedzisira inopera nemaminitsi masere pavhareji ne trazodone.
Ndiani Anofanira Kuishandisa?
Kana ukasarudza kushandisa trazodone, kune vamwe vanhu vanofanirwa kufungisisa zvakare kushandiswa kwayo.
Trazodone haifaniri kushandiswa kune vanhu vari kuporeswa kubva mukurwara kwemoyo . Izvo hazvifaniriwo kushandiswa nevanhu vanopfuura makore makumi maviri nemashanu, uye vakwegura vanofanira kushandisa mushonga nekuchenjerera. Trazodone inofanira kudziviswa kana uri nepamuviri kana kunyamwisa.
Trazodone ingave isina kukodzera vanhu vane zvirwere zvepfungwa, kusanganisira bipolar chirwere uye schizophrenia, uye kune avo vari pangozi yekuzviuraya. Shandisa trazodone nekuchenjerera kana une mwoyo kana chirwere chinonzi cerebrovascular, kukanganisa, kana zvinetso zvepvo kana chiropa.
Trazodone ine mikana yekubatana nemamwe mishonga yakawanda, saka mishonga yako inofanira kunyatsoongorororwa nemutano wako wehutano usati watanga kutora trazodone. Hapana rufu kana mwoyo zvinetso zvakataurwa kune vanhu vari kutora trazodone voga. Kuisa mishonga pakarepo kunofanira kudziviswa; panzvimbo pacho, inogona kudikanwa kuiswa pasi pakatariswa kwechiremba.
Nharaunda Dzakabatana
Pane zvakawanda zvinogona kuve nemigumisiro yemimwe mishonga. Kunyange zvazvo munhu asingadi kutarisirwa kuti ave nemigumisiro yakawanda (uye inogona kunge isina chimwe chei), asi zvimwe zvingaitika kakawanda ne trazodone zvinosanganisira:
- Kurara
- Chizutu
- Lightheadedness
- Dry mouth
- Headache
- Chiratidzo chakasvibiswa
- Nausea kana kurutsa
- Kutya
- Kuneta
- Constipation
- Palpitations
- Rapid moyo rate
- Low blood pressure
- Kuita kweganda, zvakadai sekumhanya
- Kusanganiswa
- Uturu hunorwadza
- Weight changes
- Diarrhea
- Kutya (shakiness)
- Matambudziko ane kufamba kana kubatana
Zvingave Zvingaitika Zvikuru
Nekushandiswa kwemishonga chero ipi zvayo, kunewo njodzi dzekukuvadza migumisiro. Izvi zvinowanzoitika kakawanda. Kana uchishandisa trazodone, izvi zvinogona kusanganisira:
- Priapism (inoramba ichirwadza)
- Orthostatic hypotension (kuderera kweropa kwepamusoro pakamira)
- Abnormal moyo rhythms
- Hypertension (high blood pressure)
- Kupera
- Stroke
- Kumira kurova kwemoyo
- Extrapyramidal zviratidzo
- Tardive dyskinesia
- Hypomania / mania
- Psychosis exacerbation
- Kuwedzera kuora mwoyo
- Kuzviuraya pfungwa
- Hallucinations
- Kugumburwa
- Neutropenia (low white blood cell count)
- Anemia
- Hepatitis (chiropa chokuputika)
- SIADH (Syndrome of Inappropriate Anti-Diuretic Hormone secretion)
Kudzivirirwa Kuchengetedza Kutora
Sezvakataurwa pamusoro apa, vamwe vanhu vanofanira kushandisa mushonga nekuchenjerera kana kwete. Zvakakosha kuti iwe uongororwe nachiremba wako semishonga inotanga kana kuchinjwa mumutengo. Kunyanya, zviratidzo zvekuzviuraya kana tsika dzisina kujairika dzinofanira kuongororwa.
Kana iwe uchinge uine matambudziko, unofanirwa kunge uine hukama hwepedyo nehutano hwehutano hwako. Kana kusuruvara kuchiramba kuchiita , funga kuigadzirisa nekushandiswa kwekufunga kwehutano hwehutano hwekushaya hope (CBTI) .
Shoko kubva
Kana iwe ukaona kuti kushaya hope kwakabata, zvichiita kuti kuongororwa kwezvirwere zvekurara kusanganisira mishonga yemishonga yakafanana ne trazodone, funga kudiwa kwekuongororwa nebhodhi-yakagadzirirwa kurara. Kushungurudzika kwehope, kusanganisira chirwere chokurara, zvinowanzoita kuti pave nehutano kurara usiku hwose. Kurapa kwechiitiko ichi kunogona kubvumira kusuruvara kugadzirisa. Uyezve, mamiriro ezvinhu akaita sehope dzomukati dzinogona kukanganisa kushanda kwemishonga uye kutungamirira kumigumisiro yenguva refu kana ikasara isina kutorwa kana kuvharwa nemishonga. Nenzira yakanaka, mushonga unoshanda unogona kubvumira kuvandudza apo uchidzivisa kuenderera mberi kwekuda kwemishonga inogona kukuvadza.
Sources:
Cooper, DH et al . Bhuku rinonzi Washington Manual of Medical Therapeutics. 32nd edition, 2007. 14. Lippencott, Williams & Wilkins . New York.
> Katzung, BG. Basic & Clinical Pharmacology . 9th edition, 2004. The McGraw-Hill Companies, Inc. New York.
> -Sateia MJ et al . "Clinical Practice Guideline ye Pharmacologic Treatment of Chronic Insomnia muVanhu Vakuru: An American Academy of Sleep Medicine Clinical Practice Guideline." Journal of Clinical Sleep Medicine . 2017; 13 (2): 307-349.
> "Trazodone." Epocrates Rx Pro . Version 16.4, 2016. Epocrates, Inc. San Mateo, California.