Kudya, mishonga uye zvakawanda zvinokonzera varfarin dosages
Kana iwe wakabatwa nehutachiona hwehupenzi hwakanyanya , iwe unogona kutarisira mwedzi mitatu yekupfuurira anticoagulants kana ropa-kudonha mishonga mushure mokubva muchipatara.
Dambudziko rehutano hwepfungwa inonyanya kukanganisa apo muviri wako unogadzira mucheka, kazhinji mumugumbo, unogona kukanda mamwe mazamu anogona kuvhara kupararira kumapapu ako.
Ichi chiitiko chinouraya chinozivikanwa se pulmonary embolism. Nekuenderera mberi kweanticoagulant therapy mushure mokunge muchibva muchipatara, unoderedza dambudziko rekuchinja mararamiro akadaro anouraya. Yezvinyorwa, anticoagulant therapy haisi kungopiwa nehupamhi hwehutachi hweshu. Semuenzaniso, kana iwe ikozvino uri kurapwa nokuda kwekurohwa kana imwe mamiriro ekushaya hutachiona, unogona kutarisira nguva yeupenyu hweanticoagulation.
Anticoagulation inogona kuchengetedzwa nemishonga yakawanda kusanganisira pasi-molecular-weight heparin (subcutaneous injection), fondaparinux (subcutaneous injection) kana muromo Xa inhibitors sa dabigatran. Muchikamu chino, tichafunga nezvehondo waradin (Coumadin) iyo inowanzowanika semuromo wemishonga. Kana ukasarudza anticoagulant therapy, tapota rangarira mupfungwa kuti zvisarudzo zvinowanikwa, uye chiremba wako anogona kukurukurazve izvi zvingasarudzwa newe.
Iyo Warfarin Inoshanda Sei?
Warfarin inopesana nehupenzi hwekuvhara zvinhu izvo zvinonzi vitamini K-zvinotarisana, zvichidaro zvinoparadza nzira yekugadzirisa uye kudzivirira kuumbwa kwezvimwe zvitsva.
Kusvikira inogadziriswa, warfarin inobatanidzwa ne parenteral kana injectable anticoagulant seLovenox (enoxaparin injection).
Warfarin inowanikwa mune zvose zviri mumuromo uye muzvokugadzirira-vanhu vazhinji vanotora warfarin yemuromo. Vanhu vanotanga panenge 5 mg yemfarfarin pazuva kwemazuva mashomanana okutanga. Warfarin dose inogadziriswa kuitira kuchengetedza INR mazinga, maitiro ekugadzirisa mamiriro ezvinhu andichasangana nawo pane zvishoma, kurapwa.
Kana iwe uchida, webhusaiti www.warfarindosing.org inopa mahara warfarin-dose calculator.
Ndiani Anoda Dzinga Rakakwirira?
Nhamba yepamusoro ye warfarin inogona kudiwa kune vateveri vanotevera vanotevera:
- African American
- Obese
- Hypothyroid
- Doro rinomirira
Ndiani Anoda Kuderedza Maitiro?
Kusiyana neizvi, varwere vanotevera vanofanirwa kupiwa miviri shoma yehondo warfarin:
- Vakwegura
- Asia
- Hyperthyroid
- Heart failure
- Chiropa chechiropa
- Nhoroondo yekuvhiyiwa kukuru
- Polymorphisms muYP2C9 kana kuti VKORC1 jenesi
Mukuwedzera kune zvakataurwa pamusoro pehutano hwehutano, varfarin dosage inoshandurwa zvakare zvichienderana nemishonga yauri kutora. Somuenzaniso, phenytoin inowedzera chiito chehondo uye saka inoderedza maIner mazinga.
Iro laboratory chirongwa INR (munyika dzakawanda normalized ratio) inoshandiswa kugadzirisa nzvimbo yako yekugadzirisa uye kugadzirisa kuyerwa kwako kwe warfarin. Muvanhu vazhinji, zvizvarwa zveInR zvinowanikwa kubva pa8 kusvika ku 1.2. Vanhu vari pafarfarin vanowanzochengetwa panhamba ye INR iri pakati pe2 ne3, zvinoreva kuti varwere ava vanonyanya kuzivikanwa (vane ropa rakanyanya kudarika) kupfuura vanhu vakawandisa. Paunenge uchigamuchira anticoagulation, INR mazinga anofanira kugara achiongororwa nachiremba wako.
Zvokudya Zvinosvibisa Sei Nhamba
Nokuti warfarin inopikisa vitamini K, kudya kunowedzera mu vitamini K kunogona kuderedza ma INR mazinga.
Kunyanya, miriwo yakaoma uye mashizha inowanzove yakakura mu vitamine K. Ukuwo, mbatatisi, michero, uye zviyo zvinoderera mu vitamini K. Unogona kuramba uchinyanya kudya zvikamu zvinovaka zvemiriwo uye michero, asi, edza kuramba uchigara mune zvaunoshandisa zuva rega rega kuitira kuti mizinga yako INR isashandurwe.
Ngozi
Zvakaipa zvinokonzerwa nevefarfarin therapy zvinowanzogadziriswa nenyota, makumbo uye nezvimwe zvakadaro. Zvisinei, warfarin inowedzera dambudziko rako rekushaya ropa kana kubuda ropa rinogona kuva rakakomba (funga uropi uchituka). Kana zvikaitika zvakanyanya kuora ropa nekuda kwekurapa ne warfarin, vanachiremba vanogona kutungamirira mavitamini K kuti vabatsire kubatana kana kuvhara ropa.
Vanhu vane ruzivo rwekuvhara ropa vanofanira kungwarira pavanotora warfarin. Uyezve, paunotora warfarin, zvakanakisisa kushandisa razor yegesi uye magetsi emagetsi okudzivirira kuisa njodzi yekubuda ropa. Uyewo, iva nechokwadi chekuudza chiremba wemazino kuti iwe uri mufarfarin musati maita basa remazino.
Nokuti warfarin inogona kuwirirana nemhando dzakasiyana-siyana zvezvinodhaka nekukandira mazinga ako eNR muhavha, zvakanakisisa kuti iwe usadzivirire kune-iyo-mishonga yemishonga kana mishonga inowedzera panguva iyi pamishonga iyi.
Kana iwe kana munhu waunoda iwe uchida kutora warfarin nokuda kwehutachiona hwehupenzi hwakadzika, chironda, kana chirwere che hypercoagulable, tapota yeuka kuti anticoagulant therapy pamwe nemishonga iyi inobatanidzwa. Kuti ugadzire uye urambe wakachengetedza maitiro akanaka ekutaura, iwe uchada kushanda pamwe chete nechiremba wako uye zvinoshandiswa kuti uve wezvokudya, zvakare. Ndapota yeuka kuti urambe wakangwarira, ita mazinga ako eNR achiongororwa nguva dzose, shanda pamwe neboka rako rezveutano, uye nyatsocherechedza kudya kwako.
> Sources:
> Fogarty PF, Minichiello T. Matambudziko eHemostasis, Thrombosis, & Antithrombotic Therapy. Mu: Papadakis MA, McPhee SJ, Rabow MW. eds. Ikozvino Kurapa Kurapa Nekurapa 2015 . New York, NY: McGraw-Hill; 2014.
> Mosby's Drug Reference yeZvivhesheni ZveUtano, Kechipiri. Elsevier muna 2010.