Vanopfuura makumi mana vakave vane utachiona, vanenge 15 vakafa, vane utachiona hwebhakitiriya isu tisingazivi zvakawanda nezvazvo - Elizabethkingia anophelis.
Vose avo vane utachiona vave vanhu vakuru muWisconsin, kunyanya vakuru. Vazhinji vave vaine makore makumi matanhatu nemashanu uye vakaudzwa kuti vave nedambudziko rehutano. Vamwe vakanga vari mumisha yevakwegura, vamwe muzvipatara. Hazvisi pachena kuti zvirwere zvakapfuura zvakadini uye kuti kutapurika kwebhakitiriya kwakabatsira sei pakufa.
Izvo hazvioneki sechinetso kune avo vane utano hwakanaka uye kunze kwenzvimbo dzokuchengetedza. Epidemiologists uye lab workers - kubva kuhurumende uye CDC - vari kuedza kuona kuti izvi zvinenge zvichiitika sei.
Elizabethkingia anophelis Effects
Ichi chirwere chebhakitiriya chinogona kutungamirira kufivha, kufema kwekufemerwa, chills, uye chirwere cheganda - cellulitis - iyo inogona kusanganisira nzvimbo dzinorwadza uye dzimwe nguva dzine ruvara rweganda. Yakawanikwa mumaropa erwere nevarwere uye yakagadzira sepsis clinical picture.
Dzimwe nguva nekuda kwehutano hutano husina hutano hwakanaka, hazvisi pachena kana chirwere cheElizabethkingia chikolonizer - mabhakitiriya akawanikwa asina kukonzera zvirwere; mune mumwe munhu atove ari kurwara muchipatara, zvakaoma kutaura kana ichi chiri chakanaka kana chinokonzera matambudziko. Kana isiri mukolonizer, chirwere chacho chinobatsira zvakadini kana kuti chinokonzera hutano hutano? Inoratidzika ichi bhakitiriya, kunyange kazhinji ichionekwa sekolonizer kune dzimwe nzvimbo, iri kukonzera kukanganisa kwayo mukuputika uku kunowanikwa muWisconsin.
Iyo bhakitiriya inoita kuti vanhu varwere-kana vanorwara (inorwisa zvikuru avo vanenge vatove varwara).
Kuziva
Microbiology laboratory tests inodiwa kuti aone kana utachiona hunokonzerwa naElizabethkingia anophelis.
Kana mabhakitiriya anowanikwa muropa kana mamwe muviri wemuviri, muenzaniso wemuviri wemvura unogona kushandiswa kukura mabhakitiriya mune laboratori.
Iyo bhakitiriya inokura pamashizha akasiyana-siyana emakiratikiti e laboratori ane zvinhu zvakasiyana, kuti aone kuti mabhakitiriya anokura uye kuti haagoni kukura, pamwe chete nedzimwe mimwe miedzo, nokudaro kujekesa mabhakitiriya aripo.
Dambudziko nderokuti mabhakitiriya akakura haagoni kunge ari nyore nyore. Chiratidzo hachisi nguva dzose. Zviri nyore kutanga kutanga kuziva kana mabhakitiriya ari gram kana kuti akanaka. Elizabethkingia anophelis is gram negative. Dambudziko nderokuti mazhinji emishonga inorwisa mabhakitiriya inoshanda pamabhakitiriya akawanda e-gramu haashande pana Elizabethkingia anophelis.
Other Similar Bugs
Kune dzimwe mhuka mumutauro weElizabethkingia. Izvi zvinosanganisira Elizabethkingia meningoseptica ( inoonekwa kakawanda mune zvirwere zvevanhu ), Elizabethkingia miricola, uye Elizabethkingia endophytica.
Izvo zvose zvinonzi aerobic, nonmotile, Gram-negative tsvimbo. Mazita emabhakitiriya haana kunyorwa mumatombo. Vanowanzochinja. Mimwe yemhando idzi dzinoshandiswa kuva chikamu cheBelvobacterium .
Izvo zvipenyu zvakangofanana; 98.6 muzana yehutano hwakafanana kufanana neElizabethkingia meningoseptica uye 98.2 muzana yehutano hwakafanana naElizabethkingia miricola.
Kurapa
Elizabethkingia zvirwere zvinokonzera bhakitiriya uye inorapwa nemishonga inorwisa mabhakitiriya. Dambudziko nderabhakitiriya kazhinji haapinduri nemishonga inorwisa mabhakitiriya.
Mishonga inorwisa mabhakitiriya inopesana naro inogona kushamisa - uye yekupedzisira vanachiremba vaizosvika. Chiratidzo chekutanga chebhakitiriya (se gram-negative) chingaita kuti vashandi vezvokurapa vashandise zvinyorwa zvinodhaka nemishonga zvisingashande.
Elizabethkingia zvirwere zvinowanzosangana nemishonga yakawanda inorwisa mabhakitiriya iyo inowanzobata mabhakitiriya e gram-negative - aminoglycosides, uye β-lactam zvinodhaka, kusanganisira carbapenems. Aya mabhakitiriya ave achizivikanwa kuti awedzere maitiro β-lactamases (ESBL) uye metallo-β-lactamases. Izvi zvinoreva kuti, mabhakitiriya aya anokwanisa kurwisa mishonga inorwisa mabhakitiriya inowanzofungidzirwa, asi kazhinji kasina kukodzera, kuva "huru" huru kune mabhakitiriya.
Zvisinei, E. meningoseptica, iyo yakafanana neElizabethkingia yezvirwere is gram-negative, inoratidzika seyo inopindura kune zvimwe zvinodhaka zvinoshandiswa kwebhakitiriya re gram-positive. Izvi zvinoreva kuti, Elizabethbhekland maambukiro ave achizivikanwa kuti anopindura zvinodhaka zvakadai seVancomycin, iyo inowanzogona chete kurapa zvirwere zve gram-positive.
Pane humwe ruzivo rwakaitwa nekurapa Elizabethkingia anophelis , asi kusati kwaitika uku, mabhakitiriya akaratidzwa, asina kutanga azivikanwa mishonga inorwisa mabhakitiriya, kusagadzikana ne ampicillin, chloramphenicol, kanamycin, streptomycin, uye tetracycline.
Muchiitiko ichi, mabhakitiriya anoonekwa seBactrim (trimethoprim / sulfamethoxazole), fluoroquinolones (kufanana nevovofloxacin kana ciprofloxacin, zvichida), uye Zosyn (piperacillin / tazoctam). Kurapa kwekukanganiswa kunowanzokurudzirwa - sezvinogona kuwedzerwa kweVancomycin.
Mhosva inofanira kuendeswa kune hurumende hurumende - sezvinofanirwa nemhosva dzinokonzerwa nemaktheria akafanana. Kunyanya, mamwe marudzi eElizabethkingia kana mabhakitiriya akanangana anofanirwa kuonekwa sekunge angave asina kuzivikanwa.