New device inobata migraines mushure mokunge yatanga
Migraines zvakaoma kubata. Anti-migraine mishonga ine zvinetso zvakashata uye inowanzoshayikwa zvakanaka. Uyezve, kana inotorwa nguva dzose, mishonga inorwisa-migraine inogona kuguma nemusoro we "chronification," kana kuora musoro kunowedzera. Nokudaro, pane zvave zvichida zvikuru mukudziridza zvirongwa zvisiri zvema pharmist for a migraine, kusanganisira neurostimulation (kureva, nerve stimulation).
ICefaly chigadzirwa chekunze chetendemic nerve stimulator (e-TNS) iyo inotumira mazaisai kuburikidza ne electrode yakaiswa pahuma. Inoshanda kuburikidza nekusimudzira mishonga yeophthalmic, inova davi rezvirwere zvetatu. Imwe Cefaly yakagadzirwa kare ne FDA yekudzivirira migraine. Muna December 2017, yakasunungurwa pakurapa kwemajambure emigraines uye inogona kushandiswa mushure mokunge migraine inotanga.
Chii Cefaly Device?
Iko Cefaly chigadziro chinonzi headband chinogadzira nguva inoshandiswa iko iko kushandisa mabhairi maviri AAA. Ikozvino inoshandiswa pamusoro peganda rehuma, achishandisa electrode self-adhesive. ICefaly inokurudzira mapazi e-supratrochlear uye e-supraorbital ehephthalmic nererve, iro iro rinoshandiswa nebazi rezvirwere. Nzira dzemaitiro emitambo dzinoita basa guru mukudzivirira misoro.
Cefaly anouya mumaturo matatu: Cefaly Acute, Cefaly Prevent, uye Cefaly Dual. Cefaly Acute anobata zvakaoma migraine kurwisa.
Cefaly Prevent inoshandiswa kudzivirira migraines. Uye Cefaly Dual ine zvirongwa zvezvose.
ICefaly Acute inopa zvakasimba-maminitsi makumi matanhatu ekusimudzira. ICefaly Prevent iri pasi pfupi uye inogona kushandiswa zuva rega rega.
Maererano nevanoita, Cefaly chikwata chinowedzera zvishoma nezvishoma munguva yekutanga kwemaminitsi gumi nemashanu ekushandisa.
Munguva iyi, kana ikozvino yava yakaoma, iwe unogona kuisa bhatani kuti ugadzikane kusimba uye kumisa chero humwe humwe huwandu hwekuwedzera.
Muiti wacho anonyora zvinopesana pamusoro pewebsite yedu, iyo inoshanda kune vanhu vane:
- iyo yakagadzirirwa simbiki kana kuti chipangizo chekombiyuta mumusoro
- kutambura kubva mukurwadziwa kwekusaziva kwakabva
- chirwere chemwoyo chinonzi pacemaker kana kuti chakaiswa kana kuti chinopfekedzwa, chinogona kukonzera kupesana nekufamba, kushamiswa kwegesi, kana kufa
Iyo nzira yekuita iyo e-TNS inoshanda isiri pachena. Pakutanga, nyanzvi dzakaratidza kuti maitiro ekudzivirira maitiro anovhara mafungiro achikwira mumarwadzo ekurwadza. Zvisinei, iyi pfungwa yakange isingabatsiri nekutsvakurudza kwakawanikwa. Kusiyana neizvi, zvakataurwa kuti e-TNS inoshandura kurwadziwa kwekutambudzika mumutambo wepamusoro-pasi.
Mvumo yeDAA yeCefaly semushonga weprophylactic yakabva pamigumisiro yemitambo miviri yekuEurope: Chirongwa che PREMICE uye Chidzidzo cheEurope Post-Marketing Surveillance.
Chirongwa che PREMICE
Chirongwa chePEMEMICE chaive chiongorori chisingatarisirwi chekutongwa kweCefaly, icho chakaitwa pakati pa2009 na2011 neBelgian Headache Society. Ichi chidzidzo chaive chinotarisira, kana kuti kwenguva refu, chidzidzo chaisanganisira varwere 67 vaiva nevanenge vaviri migraine kurwisa mwedzi mumwe nomumwe.
Muchiedza ichi, kwaive nemwedzi wekutanga wekutanga wevatori vechikamu vakagoverwa kune vechokwadi kana sham (kureva, kuipa) kukurudzira. Nguva yekurapa yakagara kwemwedzi mitatu.
Heano mhinduro dzekudzidza:
- Vaya vanogamuchira Cefaly kurapwa vakawana kuderera kukuru mune zvose zvemazuva uye misoro mazuva nemwedzi wechitatu wekurapa.
- Varwere vakagamuchira Cefaly kurapwa vakawana 29.7 muzana vashoma migraine mazuva uye 32.3 muzana vashoma vemazuva.
- Mukutonga kana sham, boka, kuderedzwa kwemazuva e-migraine uye mazuva ekushaya musoro kwaive ne4,9 muzana uye 3.4 muzana, zvichienderana.
- Muboka rekuedza, kana avo vanogamuchira Cefaly kurapwa, 38.2 muzana yevarwere vakawana zvishoma ne50 kubva muzana kuderedza mumwedzi wemazuva migraine.
- Muboka rekutonga, 12.1 muzana yevatori vechikamu vakawana zvishoma ne50 kubva muzana kuderedza mumwedzi wega migraine.
- Pasi pose, pakanga paine kuderedza kuwandisa kwemazuva emigraine muboka rekuedza.
- Kunyange zvazvo zvisingaverengeki zvakakosha, avo vanogamuchira Cefaly kurapa vakashuma kuderedza kuoma kwemigraines.
- Vaya vatori vechikamu vanoshandisa Cefaly vaida 36.7 kubva muzana mishonga vashoma kuti vabate marwadzo emusoro.
- Mune avo vakagamuchira kushandiswa kwemasaisai, pakanga paine 0.4 muzana yekuwedzera kwemishonga yekurwisa-migraine.
- Kwakange kusine migumisiro yakaipa kune avo vanoshandisa Cefaly.
- Cefaly inogona kuva inobatsira zvikuru kune vanhu vane migraines yakawanda, kana kupfuura mana pamwedzi (kureva, mazuva manomwe ekuchinja migraine). Sezviri pachena, tsvakurudzo dzakawanda dziri kuitwa kuti uongorore huwandu hwevarwere.
Chidzidzo cheEurope Post-Marketing Surveillance Study
A registry yakagadzirirwa varwere vose vakawana chigamba Cefaly pakati peSeptember 2009 neJune 2012. Vazhinji vevatengi ava vaigara muFrance neBelgium. Mushure mokushandisa chigadzirwa pakati pemazuva makumi mana nemakumi mapfumbamwe, varwere ava vakabvunzwa kuti vabatanidzwe muongororo yekuongorora kugutsikana uye kunetseka pamusoro pemigumisiro yakaipa.
Zvigumisiro zvekutsvaga kwekutsvaga kwekutengesa zvakaratidza kuti vanenge 53 kubva muzana yevarwere vakagutsikana nemishonga uye vaida kuramba vachishandisa chigadzirwa. Inenge 4 muzana yevarwere vakanga vasina kugutsikana nechokushandisa. Hapana chekunyunyuta uku kwakabatanidzwa nemigumisiro yakaipa. Kunyanya, vatengi ava vakanyunyuta pamusoro pekunzwa kunokonzerwa nechigadzirwa (kureva, "kutling"), kurara panguva yemusangano, uye misoro mushure memutambo.
Cefaly nokuda kweMigraine Attack
Kubva pamigumisiro ye randomized, controlbo inonzi controlbo inonzi ACME (Acute Treatment of Migraine neZvoga zvekunze kwemaitiro emhepo), munaDisemba 2017, FDA yakagamuchira Cefaly kuti iwane kurapwa kwemigraine sezvavari kuitika. Nezvizvi zvinowedzera kukiriniki, nhamba yevanhu vane migraines vanozobatsirwa naCefaly yakawedzera gumi. Muchidzidzo ichi, pakanga paine kuderedzwa kwemazana makumi matanhatu kubva muhutano hwekurwadziwa kwemagraines, uye 32 muzana yevatori vechikamu vakanga vasina kurwadziwa mukati meawa.
Migumisiro inobva pachirwere chakazaruka ichiongorora kuchengetedza uye kubudirira kwaCefaly mukurapa kwekurwa kwemagraine kwakabudiswa mubhuku reNeuromodulation munaOctober 2017. Muchidzidzo ichi, Chou nevamwe vaishanda navo vakaongorora kushandiswa kwaCefaly mumatwere makumi matatu aive nemagraines zvimwe kana pasina kanara. Kuti zvibatanidzwe muchidzidzo, varwere ava vanofanira kunge vaine migraine kurwisa kwenguva inenge maawa matatu. Uyezve, vanhu ava havafaniri kunge vatora mishonga chero ipi zvayo yekurwisa migraine.
Kurapa naCefaly kwakapiwa kweawa imwe chete. Pakapera maawa maviri nemaviri mushure mekutanga kurapwa, vatori vechikamu vakakumbirwa kuverenga marwadzo avo vachishandisa zviyero zvinorwadza.
Maererano naKou uye vanyori vanyori, hezvino mhinduro dzeCefaly yavo yekudzidza:
Nezvekubudirira, zvinoreva kurwadziwa kwakanyanya kwakaderedzwa ne 57.0 muzana mushure meawa imwe chete yekurapa uye ne 52.8 muzana mumaawa maviri. Izvo zvakaenzana panguva iyo mbiri dzinoratidza kuti kupererwa kunorwa kwakachengetedzwa zvakanaka kweawa rinenge mushure mokuguma kwekusagadzikana kwepfungwa. Iroji yevarwere vasingashandisi mishonga yekudzikinura yaiva 100 muzana mushure maawa maviri uye 65.4 muzana mushure maawa makumi maviri nemaviri. Chiyero chevarwere vasingatori mishonga yokununura mukati maawa makumi maviri nemazana emapoka e-placebo nokuda kwemafaromicic maitiro emishonga ekurapa migraine inowanzotaurwa kuti inenge inenge 32 muzana.
Yezvinyorwa, "mishonga yokununura" inoreva mishonga inotorwa apo mishonga yekutanga inotadza kubatsira. Muchidzidzo ichi, kana sangano reCefaly rakakundikana, zvino vatori vechikamu vaizotora mishonga yokununura. Kuwana mishonga yekuponesa kwakanyorwa maawa maviri uye maawa makumi maviri nemaviri.
Mukuwedzera pakuchengetedza zvakasimba kugadzirisa migraine, Chou nevakashanda navo havana kuona zviitiko zvinotambudza, uye hapana wevadzidzi vakapopotera nezvekurapa.
Zvakaoma kuenzanisa kushanda kweCefaly nemishonga inoshandiswa kubata chirwere chemvura nekuda kwekusiyana kwekuedza maitiro pakati pezvidzidzo. Kunyange zvakadaro, achishandisa chirwere chinorwadza chimwechete, chidzidzo chakaparadzana chakawana kuti awa imwe mushure mokutora NSAID diclofenac (Voltaren), varwere vakarondedzera 26.8 kubva muzana kuderedza mukutambudzika kwekuenzaniswa ne 17.1 muzana kuderedza kushungurudzika kwemagraine kune avo vanotora sumatriptan, uye 52.7 kupera kwemazana kubva kune avo vanogamuchira sangano reCefaly.
Nezvekudya kwemishonga inoponesa, imwe tsvakurudzo inoratidza kuti pakati pe20 kubva muzana uye 34 muzana yevanhu vanoda kutora mishonga yokununura pakati pemaminitsi maviri ne24 mushure mokutora triptan. Uyezve, paavhareji, 37 muzana yevanhu vanotora NSAID vanoda kutora mishonga yokununura. Izvo, 34,6 muzana yevarwere vanowana chirongwa cheCefaly vanoda kutora mishonga yokununura.
Pakupedzisira, zvinoratidzika kuti Cefaly anoshanda pamwe nemamwe marapirwo emagraine musoro anosanganisira triptans uye NSAIDs. Kusiyana nemamwe mimwe mishonga, zvisinei, Cefaly haina matambudziko akakomba akaipa. Uyezve, vatsvakurudzi vanoratidza kuti chigadzirwa cheCefaly chinogona kunyanya kushanda kana chichishandiswa pamberi kwemaawa matatu mukurwisa.
Mamwe Mashoko Pamusoro peMigraines
Vanenge 12 kubva muzana veAmerica vanokudza migraines. Migraines inowanzoonekwa katatu muvakadzi. Maererano neHuman Burden of Disease Study 2013, migraines ndiyo yechitanhatu zvirwere zvinokonzera kuparadza munyika yese uye zvinokonzera kushaya simba kwehupenyu hwehupenyu.
Migraines inoitika mukurwiswa kwekuenzanisa kunorwadza kwakanyanya. Unhu hwehutambudzi huri kukumhanya kana kuputika-kazhinji kunobata rutivi rumwe chete rwemusoro. Munguva yekurwisana kwevanhu, vanhu vanonzwa kuwedzerwa kunzwisiswa kwechiedza uye inzwi. Migraine vanotambura vanogonawo kunetseka nekutura.
Vamwe vanhu vanonzwa kushungurudzika kwepfungwa kana zvisati zvaitika kana panguva yekurwisana kwemagraine. Iyi kushungurudzika kwekunzwa kunonzi ara. Izvi zvinokanganisa zvinogona kuonekwa, zvakadai sezviedza zvinopenya kana mapofu mapofu. Vanogonawo kuratidza sekumhanya nemaoko kana chiso.
Migraine zvinokonzera zvinosanganisira:
- Kushungurudzika
- Kufunganya
- Kusakwanisa kurara
- Kujekesa kune chiedza
- Hormonal changes
Vatungamiri vemigraines vanogona kunge vakaoma kana kudzivirira. Mishonga inoshandiswa inoshandiswa kumisa migraine kurwisa uye kudzorera kushanda kwakanaka. Kuchengetedzwa kwekuchengetedza chinangwa chekugadzirisa kurwisa kwemaitiro nekuoma.
Zvinodhaka zvinoshandiswa mukurapa kwakanyanya kune migraine zvinosanganisira:
- NSAIDs
- Analgesic
- Triptans
Heano zvirongwa zvokudzivirira zvemigraine:
- Beta-blockers (p., Metoprolol, propranolol, bisoprolol, uye candesartan)
- Calcium channel blockers (semuenzaniso, flunarizine uye verapamil)
- Anticonvulsants (semuenzaniso, topiramate uye valproate)
Nutraceuticals, kusanganisira riboflavin, coenzyme Q10, uye magnesium, vane uwandu hwakadzika mukudzivirira migraine kurwisa.
Kunyora muCephalalgia , Dodick, naMartin vanotaura nezvemigumisiro yakaipa ye triptans:
Kunyange zvazvo ichiita seboka rakafanana rezvinodhaka, zvinokonzerwa nekuita meta-tsananguro zvinoratidza kusiyanisa kwekubudirira uye kushivirira mukati memuromo we triptans. Chiitiko chechirwere chinokonzerwa nemishonga chinokonzera mishonga (CNS) nemigumisiro ine humwe hutatu hutatu hunokwana 15 kubva muzana uye inogona kuwirirana nehutachiona hwehutano uye kuderedzwa kwekubudirira. Kuitika kwezviitiko zvakashata zvinosangana ne triptans muzvizhinji, uye CNS migumisiro yakanyanya, inogona kutungamirira kunonoka mukutanga kana kuti kunyange kudzivisa kwehumwe mushonga unoshanda.
> Sources:
> Cefaly website. www.cefaly.us.
> Chou DE, et al. Kunze kweTegemgeminal Nerve Kukusimudzira kweAradio Acute Treatment ya Migraine: Zarura Dhiyabhorosi Dambudziko Mukuchengetedza uye Efficacy. 2017; 20: 678-683.
> De Novo Kuenzanisa Chikumbiro cheCefaly Device . FDA.
> A migraine. MedlinePlus.
> Rederer F, Penning S, Schoenen J. Transcutaneous Supraorbital Nerve Kusimudzirwa (t-SNS) neCefaly [1] Dhiyabhorosi yekudzivirira Migraine: Kuongorora kweZviwanikwa Zviripo. Pain uye Therapy. 2015; 4: 135-137.