Rinowanzoshandiswa mazuva ano, mavara emumunda mavaraira rudzi rwemishonga inonzi radiation inoshandiswa kuHodgkin's lymphoma iyo yakabatsira kuwedzera kurapa kwemaawa muma1960.
Mishonga inopihwa munzvimbo yakawanda yemutsipa, chifukidzo, uye mapfupa ekuvhara nzvimbo dzose dzedzimba dzenhengo dzemuviri. Chimwe chemapapu, mwoyo nemapfudzi akanga akadzivirirwa kubva padanda remhepo kuti aderedze migumisiro yechirwere.
Izwi rokuti 'mantle' rinobva muzita rejira, kufanana nejasi, rakashandiswa makore mazhinji kumashure. Chimiro chenzvimbo yakajeka-iyo mashizha-ane mitsara inofanana nechidziro chekudzivirira.
Iko rudzi rwemasango makuru emisipiresi haruwanzoshandiswi nhasi. Zvisinei, mashomanana makumi emakore akadzoka, apo chemotherapy yakanakisisa yehutano hweHodgkin's lymphoma yakanga isingawanikwi, nzira iyi yakashandiswa kubudirira kurapa nhamba yakawanda yevarwere vane chirwere cheHodgkin's early-stage. Nekufambira mberi mukurapa, chemotherapy regimens iko zvino inoshandiswa kune varwere vose uye kupisa kwemhepo kunongowanikwa kunzvimbo duku yaimbove yave yakakura node - imwe nzira inonzi inosanganisira mashizha emhepo.
Kwete kuti urege kuvhiringidzwa ne: Mantle cell lymphoma
Mantle emhepo mashizha haavi nechokuita ne mantle cell lymphoma , rudzi rwemusiri Hodgkin lymphoma.
Nhoroondo
Kudzoka kuma1960, Hodgkin lymphoma yakanga yakaipa seyemapapu emapapu nhasi, sezvakataurwa naHodgson mumagazini yaDecember 2011, "Hematology, ASH Education Program." Imwe nzira inozivikanwa seyendaneti yakawanda yakarapwa yakapa mushonga wokutanga wakavimbika nokuda kwekutanga kwemawere Hodgkin chirwere, asi vakapona vakave nemigumisiro yemigumisiro kubva mumakore ekupedzisira emvura, kana kunonoka kutyisa, kusanganisira chirwere chemwoyo uye kenza yechipiri.
Apo izvi zvakazozivikanwa, basa rakatanga kuvandudza zvirwere zvekutarisa nekuderedza kuora. Kuvandudzwa kwehutachiona hwehutachiona hwekutengesa uye kushandiswa kwayo pamwe chete nemakemikrasi ano mazuva ano anotarisirwa kuunza kukonzera kukuru muzviitiko zvekupedzisira.
Kanzvadzi yeChechi Inotevera Mantle RT
Ngozi yekenza yemazamu ichitevera mantle emhepo inonzi radiation therapy (RT) yeHodgkin lymphoma yave yakanyanya kunetseka.
Mantle RT kune lymph nodes yemakumbo, chifuva, nemutsipa-kana axillary, mediastinal, uye mhondi yekervical-inobatanidza ne 2 kusvika ku20-yakawedzera ngozi yechirwere chepachifu, zvichienderana nemakore ekurapa. Nyanzvi dzakawanda dzakaona kuti njodzi yakakwirira kune vakadzi vanobatwa vasati vava nemakore makumi maviri. Kansa yebonde inokwana 40 muzana yemukondombera yechipiri pakati pevakadzi vanopona.
Dambudziko reMwoyo uye Mantle RT
Mishonga inogona kunge inokuvadza mwoyo nenzira dzakasiyana-siyana. Zvimwe zvidzidzo mumhuka zvakaratidza kuti miviri inogona kukanganisa kupopota kwemaitiro anoita kuti maronary artery plaques inogona kukura kana kuti yakaipisisa yakambosimbiswa. Chimwe chiitiko mushure mekubuda kwemazizi kungave kuwedzera kwepakati mukati meimwe yemidziyo yeropa iyo inowanzopa mwoyo musumbu.
Enda mberi
Nyanzvi dzezviongorori dzinosimbisa kukosha kwekuongorora zvirwere pamatambudziko emagumisiro ekupedzisira-kubuda kune zvinodhaka kubva kuHodgkin lymphoma mishonga yemakore akapfuura.
Kuchinja kukuru mune chemotherapy uye remishonga yakashandiswa pakurapa Hodgkin lymphoma pamusoro pe 10-20 yekupedzisira inotarisirwa kuita kuti zvive zvakasiyana-siyana-zvinyorwa zvinyorwa pane izvo zvingave zvakajairika zvichibva pane zvidzidzo zvezvino zvekupedzisira.
Sources:
American Cancer Society. Radiation therapy yeHodgkin chirwere.
Schaapveld M, Aleman BM, van Eggermond AM, et al. Kenza yechipiri ingozi kusvika makore makumi mana mushure mekurapwa kweHodgkin's lymphoma. N Engl J Med . 2015; 373 (26): 2499-511.
Hodgson DC. Zvichaitika munguva yemazuva ekurapa kwemazuva ano eHodgkin lymphoma. Hematology Am Soc Hematol Dzidzo Yedzidzo. 2011; 2011: 323-9.