Tsanangudzo:
Kusiyanisa kunoreva kune zvakatevedzana matanho ayo sero rinopfuura naro kuti rive rakakura. Sezvo sero inokura, inotanga kuratidza chinangwa chayo uye basa mumutumbi wemunhu, nzira inozivikanwa sekusiyanisa.
Mitsara inogona kuva isina muviri nokuti iri kukura nokukurumidza kubva pakatanga mutsva, zvakadai mukugadzirwa kwecheche mudumbu; asi masero mashoma asina kusiyanisa anowanzoitikawo kuvanhu vakuru - somuenzaniso, mumatumbu uye nhengo dzinogara dzichishandura masero ekare nezvitsva, zvakadai semafuta emapfupa.
Kusiyanisa zvizere masero ndiyo yatinodzidza pamusoro pezvinyorwa zvebhaibheri: masero matsvuku eropa, masero europi kana neuroni kana masero masero, somuenzaniso. Kusiyanisa ndiyo nzira inogadzirisa mafungiro esirivha esirivha, inosarudza sero iri rakasiyana uye rinoguma mumamiriro ezvinhu chaiwo akafananidzirwa nechinangwa chevakuru chesaini. Girasi reganda harisi sechitema cheropa, semuenzaniso. Rimwe sero rakakura, rakanyatsosiyaniswa rinowanzove nebasa rakajeka rinofanira kutamba, rine maitiro anowanzoitwa nhengo kana mhuka iyo inorarama.
Kusiyana muCancer
Mukenza, nzira yekusiyanisa inogona kuitika isingaitiki. Kanzera dzemawere dzinogona kubatanidzwa mune rimwe chikamu chekusiyanisa, dzinogona kunge dzisina kusimbiswa uye dzinogona kushanda pamwe chete nemasero akakomba, ane utano. Mune dzimwe nguva, dzimwe nguva masero aya haana kusiyaniswa zvakanyanya zvokuti, pasi pema microscope, havatomboita semasero avakagadzira kubva.
Vanachipatara ndivo vanachiremba vanodzidziswa kuongorora masero nematukisi, zvakadai seaya anotumirwa muzvipikisi zvinonzi biopsy, kugadzirisa nezvezvirwere. Yaiwanzove yekuti ma-pathologist aivimba zvakanyanya pane zvinonzi morphology - kuti masero akatarisa sei pasi pe microscope: ukuru, chimiro kana hupfumi hwemavara apo dyesi dzakasiyana uye tsvina zvakashandiswa.
Izvi zvichiri kuitika, uye zvinopa ruzivo rwakakosha pamusoro pekuparadzanisa, asi ikozvino pane zvimwe zviedzo zvinoshandiswawo zvakare. Iyi miedzo inogona kujekesa mamolekemu chaiwo kunze kwemasero anokwanisa kushandiswa kuti ataure kuti zvakajeka sei sero.
Kusiyana muRopa Cancers
Chimwe chezvikonzero nei kune marudzi akasiyana-siyana e-lymphomas ndeyekuti masero ezvirwere zvemasimba ane zvikamu zvakawanda zvekukura, kuyananisa nekukura. Kana iwe wakambodzidza nekuvandudzwa kwemasero eropa, kana hematopoiesis , unoziva kuti haisi chinhu chisinganzwisisiki - kune zvikamu zvakasiyana siyana uye marudzi akasiyana emuviri masero.
Mune mhaka yekenza yeropa yakafanana nerukemia kana lymphoma , masero eropa eropa ane kenza kana lymphocytes inowanikwa "nenzira yakasiyana kwazvo" iyo. Kana kenza inowanzoitika, inowanzo "kuvhara" sero - uye yese yevana vanorwara nekenza - muchikwata chekufambira apo kenza yakatanga.
Zvisizvo zvakasiyana-siyana masero anogona kunge akafanana nemasero ekutanga avakagadzira, asi angave asingakwanisi kuita mabasa ose anotarisirwa emasero emuviri akanaka. Mitsara iyo haina kusiyaniswa zvakanyanya ishoma kukura, inogona kukura nokukurumidza, uyewo kazhinji inowanzoita chemotherapy.
Zvakanyatsosiyanisa masero anenge akafanana nemasero akakura uye saka anowanzoparadzanisa nekukura zvishoma nezvishoma. Masero anonyadzisa akaparadzaniswa zvakanaka, kufanana nevamwe vavo, vanowanzokura zvishoma nezvishoma.
Mune zvimwe zviitiko, ruzivo pamusoro pekuparadzanisa runogona kukanganisa kufungidzira nekuzivisa chisarudzo chekurapa. Pakati pese, "zvakanyatsosiyaniswa" zvinoshandurirwa kumuchechi wepamusana wekenza, asi "kusiyaniswa zvakasiyana" kunoshandurwa kune imwe yepamusoro-bharayi.
Kusiyanisa uye Kuenzaniswa Kwekenza Yeropa
Maitiro akawanda akasiyana-siyana akashandiswa kwekenza yeropa mumakore.
Ikozvino maitiro ehutano, yehutano hweWorld Health Organization (WHO), inotora zvinhu zvakasiyana-siyana kuti zviongorore kuitira kuti uone rudzi rwekuipa, uye kuparadzaniswa chimwe chezvinhu izvi.
Kana zvichibvira, izvi zvinyengeri zvinorondedzerwa ne "dzinza" ravo ku:
- Myeloid neoplasms
- Lymphoid neoplasms
- Histiocytic / dendritic neoplasms
Kusiyana mukati mechikamu chimwe nechimwe kunokosha zvakare. Semuenzaniso, lymphomas ndiwo kanzira dzemakirinikiti, ayo anowira muzera re lymphoid neoplasm . Kune B lymphocytes uye T lymphocytes. Ngatiti iwe unoziva kenza yako ndeyeB lymphocyte lineage, kana B-cell lymphoma .
Iwe unogona kuva nemakukutu B cell lymphomas, iyo inopindirana nezvikamu zvezvakagadzirwa zveB cell kukura nekukura. Iwe unogonawo kuva nechepamberi B lymphoblastic leukemia / lymphomas - aya ndiwo kanzura yemasero masero akazvipira kuva nhengo dzemhuri yeB-cell.
Kusiyanisa uye Ropa reKenza Kurapa
Izvo zvisina kusiyaniswa lymphoma inogona kunge ichikura nokukurumidza uye inowanzosvika chemotherapy iyo inoshandiswa inoparadzanisa masero.
Imwe muenzaniso wekusiyanisa iyo inogona kushandiswa kumushandi wevarwere inowanikwa muacute promyelocytic leukemia, kana APL. Izvi zvinopesana nedzimwe mhando dze AML nenzira dzinokosha. Chimwe chazvo ndechekuti, apo APL masero akaparadzwa ne chemotherapy, anosunungura mapuroteni anogona kukonzera miviri ye-blood-clotting nzira yekubuda-yeku-kutonga, iyo inogona kuuraya.
Masayendisiti akawana kuti APL masero anogona kuiswa coaxed kuti achinje kuva masero masvikiro akakura nemamwe madhiragi. Sezvo kubatana uku kuri kunyatsosiyanisa, mishonga iyi inonzi mazita ekusiyanisa. Sezvo kuora kwekukura kusingafi nerudzi urwu rwemishonga, mapuroteni anokuvadza anoramba ari mukati memasero, uye kuvhara kwekugadzirisa hakugoni kubuda.
Yakapedzwa muna February 2016, TI.
Sources:
Vardiman JW, Thiele J, Arber DA, et al. Kuvandudzwa kwe2008 kweWorld Health Organisation (WHO) yakarongeka yezvinyorwa zvisingagadziriswi uye yeukemia yakaoma: maonero uye kuchinja kunokosha. Ropa. 2009; 114: 937.
American Cancer Society. Mamwe madhiragi anokonzera myeloid yeukemia yakaoma. Yakasvika muna February 2016.
Gribbon, J., Loescher, L. Biology yeCancer muJarbro, C., Frogge, M., Goodman, M., Groenwald, S. (2000) Kurapa kweKenza: Maitiro uye Maitiro 5th Ed Jones naBatlett: Sudbury, MA . pp. 17- 35.