TSH Ndiyo Muedzo Wokuedza Kuongorora nekuona Chechi yeHiroid
Kushandura TSH mazinga hausi kunyatsogadzikana, naizvozvo hausi wega kana uri kushamisika kuti mazinga e thyroid anorevei , uye kunyanya zvakakosha uye pasi pasi maTSH zvinoreva kurapa.
Semuenzaniso, unogona kubvunza kuti chikonzero chiremba wako anoda kuderedza pane kukura mishonga yako yehutachiona apo tsvina yako yeTSH iri pasi, kana, zvakare, nei chiremba wako achiwedzera mishonga yako yehutachiona kana TSH yako yakakwirira.
Iva nechokwadi chokuti, kunyange zvazvo zvingaita sechemberi, zvose zvinonzwisisika paunotarisa biology yehutachiona yekugadzirwa kwehomoni.
Thyroid Basics
Thyroid thyland gland inobereka hormone ye thyroid. Kana ikashanda zvakanaka, utachiona hwako humwe chikamu chezvinyorwa zvinopikisa nepituitary gland inosanganisira matanho anoverengeka anokosha:
- Kutanga, pituitary yako inonzwa hutachiona hwetachiona hunosunungurwa muropa.
- Huru yako inosunungura mutumwa chaiye hormone: utachiona hunokurudzira hormone (TSH). Basa reTSH nderokukurudzira utachiona kuti ubudise hutoni yakawanda.
- Apo utachiona hwako, pane chero chikonzero-chirwere, kushungurudza, kuvhiyiwa, kana kuvhiringidzika, somuenzaniso-hausi kana kuti haugoni kubereka hormone yakakwana yehutachiona, pituitary yako inowona kuderedzwa kwehutachiona hwetachiona uye inotanga kuita chiito nekuita zvakawanda TSH, izvo zvino zvinoita kuti utachiona wako huve nehutori hwehutori. Iyi ndiyo miitiro yepituitary yekusimudza maitiro ehomoni yekemikari uye kudzorera iyo nzira kuti iite zvakanaka.
- Kana utachiona hwako hwakanyanyisa uye huchibudisa hutoni hwakawanda-hutachiona-nekuda kwezvirwere, kana kutora kukwirira kwakanyanya kweyero yehomoni yakashandura zvinodhaka-zvinonzi pituitary manzwiro ako kune huwandu hwakawanda hwetoriyasi inofamba uye inopedza kana kudzivisa kutema TSH. Iyi inodonha muTSH ndeyekuedza kudzoka kutenderera hutachiona hwehutachiona hunoenderana.
Kududzira TSH Nhamba
Kana ukangonzwisisa zvidzidzo zvehutachiona izvi, zviri nyore kunzwisisa zvinoshandiswa neTSH yakadzika uye yakakwirira TSH inoratidza nezvehutachiona hwebasa rako.
Sezvo TSH inokonzera utachiona hwehutori uye hunochengetedza sarudzo yacho yakaenzana:
- A high TSH inoratidza kuti utachiona hwako huri kushaya simba (hypothyroid) uye husingaiti basa rekubudisa hutoni yakakwana yakakwana. Iyo yakawandisa TSH iri kushanda kuita kuti utachiona hwako huve nehutoni hutoni.
- A low TSH inoratidza kuti thyroid yako yakanyanyisa (hyperthyroid) uye inokonzera kutapira kwehomori yehomoni. Plandish gland iri kudzvinyirira TSH kuitira kuti utachiona hurege kubereka zvimwe.
Is TSH Yakavimbika here?
Panguva yekuongororwa, vanachiremba vazhinji vanoshandisa muedzo weTSH kuti uongorore utano hwako hwetachiona uye uone nzira yakanakisisa yekurapa.
Cherechedza, zvisinei, kuti vamwe vashandi vanofunga kuti kuvimba chete neTSH, pasina kuongorora mazana emakiromoni ehutachiona chaiwo, sa free thyroxine (T4), angave asingakwanisi kuona zvinetso zvehutachiona zvisinganzwisisiki.
Semuenzaniso, pachena T4 kuwedzera kune TSH inowanzoedzwa kana chiremba anokonzera utachiona husina kunaka hunobva kuchirwere chepituitary gland kana hypothalamus. Saizvozvowo, kana TSH yakajairika, asi munhu achiripo ane zviratidzo zvekuva hyperthyroid kana hypothyroid, T4 yakasununguka inogona kuongororwa.
TSH hainawo kukwanisa kuongorora hypothyroidism panguva yekudzivirira , saka nei pasina T4 uye / kana kuti T4 yakawanda inotariswawo.
Zvichienderana nezvipatara mamiriro ezvinhu, mamwe maitiro ehutachiona anogona kuongororwa anosanganisira triiodothyronine (T3), kutenderera T3 , uye kuongorora kweanoripikisi.
TSH Refer Ranges
Chirwere chikuru mukubatana kweTSH ne hypothyroidism uye hyperthyroidism inopfuurira kusagadzikana munyika yezvechiremba pamusoro peongororo yekutarira kweTSH muedzo.
Nhamba dziri pasi apa 0.4 dzinofungidzirwa kuti zvinogona kuitika zve hyperthyroidism, uye mazinga ari pamusoro apa 5.0 anowanzofungidzirwa kuti zvinogona kuitika zve hypothyroidism, asi dzimwe nyanzvi dzinonzwa kuti urwu hwakareba zvakanyanya uye kuti hunofanira kutapudzwa kusvika 0.4 kusvika 2.5mU / L.
Kusarudza Zvirwere Kubva paTSH
Paunenge uchirasikirwa ne hypothyroidism ne thyroid hormone replacement mishonga, vanachiremba vanoedza kuedza kukurapa iwe mu "inowanikwa" mararamiro eTSH kubva ku 0.3 / 0.5 pamucheto-ekupedzisira, kusvika ku 3.0 / 5.0 kumusoro.
Saka, paunenge uenda kunoongorora uye TSH yako inouya pasi pemazuva ose (izvo zvinoreva kuti TSH iri kudzvinyirirwa nokuti utachiona hwehomodhoni hwakatove hwakakwirira), chiremba wako angada kuderedza kuyerwa kwako kwetachiona hormone nokuti watova hyperthyroid . Izvi ndezvokuti kuderedza kudzvinyirirwa kweTSH (kureva kukwirira kwetachiona hormone production) kunogona kuwedzera mukana wevanhu wepill fibrillation (umutima arrhythmia) kana osteoporosis.
Uye kana chirwere chako cheTSH chichiuya pane zvinowanzoitika, vamwe vanachiremba vanoda kuwedzera miviri yako yehomoni yehutori, nokuti mazinga ari pamusoro pemazuva ose anofungidzirwa kuti angava hypothyroid (asingashandi).
Shoko Rinobva
Muchidimbu, muedzo weTSH ndiwo madhavhiro ekutsvaga ropa anonyanya kushandisa kune zvose zviri kuongorora hypothyroidism uye hyperthyroidism uye kutarisa utachiona hwemajoni replacement therapy (kana zvichidiwa).
Kunyange zvazvo mamiriro ezvehutano, sekuita pamuviri kana kupinda muchipatara, zvingada kuti T4 neT3 zvienzaniswe, kunzwisisa chikonzero chekuda kwemazinga akakura kana kuti pasi pasi kweTSH inoreva kuti utachiona hwako huri nyama chaiyo yaunoda kuziva.
Izvozvo zvakati, kana iwe uine mibvunzo pamusoro pebasa rako reropa rehutachiona, iva nechokwadi chekubvunza chiremba wako.
> Sources:
> Bahn, R., Burch, H, Cooper, D, et al. Hyperthyroidism uye Zvimwe Zvikonzero Zvako Thytotoxicosis: Mazano Ekutungamirirwa kweAmerican Thyroid Association uye American Association of Clinical Endocrinologists. Endocrine Dzidzira. Vol 17 Nha. 3 Mbudzi / June 2011.
> Braverman, L, Cooper D. Werner & Ingbar's The Thyroid, 10th Edition. WLL / Wolters Kluwer; 2012.
> Garber, J, Cobin, R, Gharib, H, et. al. "Clinical Practice Guidelines for Hypothyroidism muVakuru: Cosponsored neAmerican Association of Clinical Endocrinologists uye American Thyroid Association." Endocrine Dzidzira. Vol 18 Nha. 6 November / December 2012.
> Ross DS. (2017). Kuongorora kwehutachiona hwebasa. Mu: UpToDate, Cooper DS (Ed), UpToDate, Waltham, MA.