Dzidza Nekuedzwa Kwakaiputirwa neCystic Fibrosis

I sweat test yave iri muedzo wekusarudza kuongorora cystic fibrosis (CF) kubva muna 1959. Nzira itsva, dzakadai sekuongorora mazita , dzakagadzirwa asi mumamiriro ezvinhu akawanda, chirwere che sweat chiri chiitiko chinotungamirira kuCF kufungidzirwa. Zvimwe zvikonzero zvekuve nechidzidzo che sweat ndezvekuti:

• Mwana akave nekuona kuzvarwa patsva kweCF
• Munhu wezera ripi neripi ane zviratidzo zveCF

Chii Chinoitika Panguva Yokuedzwa Kwekupika

I swe swee test inowanzoitwa nechemberi, asi inogona kuitwa pachidya checheche nevana vane maoko maduku.

• Nhanho Yokutanga - Kukurudzira Kufutira: Muyanzvi anoisa magetsi maviri ane swet-inducing drug inonzi pilocarpine paganda. Chinhu chiduku chemagetsi chinobudiswa kuburikidza nemagetsi ekubatsira pilocarpine kukurudzira kutuka. Ikozvino haisi inorwadza, asi kunonoka kwekunzwa kunonzwa kunogona kunzwa.
• Yechipiri Chekutanga - Kuunganidza Kufugama: Mushure memaminitsi gumi, technician inodzivisa ikozvino uye inobvisa magetsi. Ganda rinobviswa rakaoma uye chidimbu chepurasitiki yakafukidzwa nemapurasitiki, dzimwe nguva anonzi "sweat patch" inowanikwa panzvimbo yekuunganidza jira. Apo chiyero chakakwana chokujaira chinounganidzwa, kazhinji pamaminitsi makumi matatu nemakumi mashanu nemashanu, pepa rinoputika-sweta rinobviswa uye rinotumirwa kubhi rekuedzwa.

Ikoko Kuedza Kunotsvaga Kutarisa

Vanhu vane cystic fibrosis vane yakakwirira yemunyu, inozivikanwa se sodium chloride, mu sweatshi yavo.

I swe swee test inoyera zviyero zve sodium uye chloride mu swe sweat, asi chiyero chekloride ndicho chinokonzera kuguma kwemuedzo.

Chloride Ranges mucheche

• pasi pemakumi matatu = chikara
• 30 - 59 = kumucheto
• 60 kana kupfuura = yakanaka kune CF

Chloride Ranges muvana nevakuru

• pasi pemakumi mana = yemazuva ose

• 40 - 59 = kumucheto
• 60 kana kukura = yakanaka kune CF kuvana, asi inogona kunge yakagadzirwa nevanhu vakuru. Kana munhu mukuru ane chigumisiro chinenge 60 mmol / litita, kuongorora mazita ega kunogona kuitwa kuti kusimbise kuongororwa.

Kururamisa Kwakaitwa Kuzvinyima Kwakadini

I swe swee test is 98% yakarurama, asi zvimwe zvikonzero zvinogona kuita kuti mhinduro dzisakarurama kana dzisina kukwana.

• Nhema dzenhema: Zvimwe zvinetso zvisinganzwisisiki zvinogonawo kubudisa yakakwirira ma chloride muhutu, asi zvinetso izvi zvine zviratidzo zvakasiyana neye cystic fibrosis. Kana kuedzwa kwe sweat kunobereka migumisiro yakanaka mumunhu ane zviratidzo zvisingaiti zveCF, zvakare kuedza kunofanira kuitwa kuti kusimbise kuongororwa.
• Nhema dzenhema: Dzimwe nguva, munhu ane cystic fibrosis achava nechirwere chekloride chaiyo mu sweatshi rake. Kana izvi zvikaitika, kazhinji zvinenge nokuti hazvina kukwana kurapa kwakapiwa muenzaniso, kana jira rakanyudzwa.

Mafungiro Enhema Mazhinji Anowanzoonekwa

• Vacheche vasati vhiki mbiri vakura kana kuti vanorema pasi pe7 pounds avo vangave vasingakwanisi kubereka sweat yakakwana.
• Vanhu vane kuzvimba kwemaviri kunokonzerwa nekuchengetedza kwemvura, inozivikanwa seEdema, iyo inofungira inogona kudimbiswa neyemasukirusi.

_Chinhu

_{Mishra, A., Greaves, R., naMassie, J. "Kukosha kwekutuka kwekutuka kweKutsvaga kweCystic Fibrosis muGenomic Era". 2005. Clinic Biochem Rev. 26 (4): 135-153. 20 July 2008.}