NIH Kubatanidzwa neHypothyroid Varwere Vechidzidzo Chitsva
Zuva rinofadza kune varwere vetachiona, uye rimwe rave rakamirira kwenguva refu. Sangano reNational Institutes of Health reUnited States rakazivisa kuti kuongororwa kwekliniki kwave kuchangotangwa muna 2012 kuWalter Reed National Military Medical Center, muBhetesda, MD, kuti iongorore zvakasikwa zvinodhaka zvehutachiona zvinopesana nev levothyroxine, pakurapa kwepakutanga hypothyroidism.
Kuongorora-kutarisa-kuongorora-kunozopfuura munaMeyi wegore ra2014 - kuchaongorora maonero ekuti hypothyroid varwere pane zvakasikwa zvehutachiona (izvo zvinonzi "svondo rinodonhedzwa" kana kuti DTE) zvinogona kuva "nekuderera kwezviratidzo, kunatsiridzirwa kwekunzwisisa, uye kuwedzerwa mupfungwa yekugara zvakanaka / hupenyu hwehupenyu , "kana uchienzaniswa ne levothyroxine.
Zita guru rekudzidza nderokuti "Yakarongedzwa neTyroid Extract Kuenzaniswa naLeviothyroxine muTransment of Hypothyroidism : A Randomized, Double-blind, Chidzidzo cheCrossover," uye vari kuunganidza vatachiona sevanodzidza.
Eligibility
Iwe unokodzera kubatanidzwa muchidzidzo ichi kana iwe uri murume kana mukadzi, pakati pe18 ne65 wemakore. uye ave pa levothyroxine yepamusoro hypothyroidism kwemwedzi inenge mitanhatu. (Cherechedzai: Nhengo dzinoshingaira kana kuti dzakasimuka pauto rehondo uye avo vanowana zvikodzero dzinokodzera izvi.Exclusions
Iwe uchave wakabviswa kubva pachidzidzo kana une chero chezvinhu zvinotevera kana nyaya:- pamuviri kana chirongwa chekuzvitora mumwedzi 12 inotevera
- chirwere chepfungwa , kunyanya kuronta arteri chirwere
- chronic obstructive chirwere chemapapu
- malabsorption disorder
- masimba ekuvhiya
- kunyanya kuora kana chiropa chisina kukodzera
- kugadzirisa matambudziko
- utachiona uye kwete-utachiona hunoshanda kanzira
- kusagadzikana kwepfungwa
- psychotropic kushandisa mishonga
- steroid use
- amiodarone use
- chemotherapy nokuda kwekenza
- simbi inowedzera kupfuura 325mg pazuva
- carafate / proton pump inhibitor use
- cholestyramine use
Nei Ichi Chiedzo Chikosha?
Uyu muedzo unokosha nekuti ndiyo nguva yokutanga munhoroondo yemazuva ano kuti ndinoziva kuti sangano rekutsvakurudza rezvechiremba rinozivikanwa munyika yose - munyaya iyi, US National Institutes of Health - iri kuita kaviri-mapofu, kutsvaga kutsvaga kuenzanisa zviratidzo, kugona kuita basa, hupenyu hwakanaka, uye hupenyu hwehupenyu mu hypothyroid varwere pane zvakasikwa zvinoshandiswa nehutachiona hwehutachiona , zvichienderana neanowanzonzi levothyroxine.Uyu muedzo unokosha zvakare nokuti pane kusarura kwakasimba pakati pevanhu vanowanzogadzirisa endocrinologists pakurondedzera kushandiswa kwemasikirwo emakemikari echisikigo, asi haisi maererano nekutsvakurudza, asi pane, maonero avo uye zvavanoda. Zvimwe magumo ekupedzisira, chaizvoizvo, akatotaura zvakare kuti maitiro ehutachiona echisikiro seSimba anongotorwa chete ne "fringe" , pasinei nokuti mitsara inopfuura mamiriyoni maviri emishonga iyi inyorerwa gore rega rega muUnited States chete, uye zvakapoteredza nyika.
Uyu muedzo unokosha zvakare nokuti tinoda tsvakurudzo iyo inotarisa zvakananga kushandiswa kwezvisikwa zvakasikwa zvekirori. Zvimwe zvidzidzo, kusanganisira 2009 Danish chidzidzo , zvakaratidza unhu hwekuvandudza hupenyu pamwe nekuwedzera kwekugadzira T3 yekugadzira T4 (levothyroxine), asi vamwe vanachiremba vakataura kuti zvidzidzo izvi hazvibatsiri patinofunga nezvemhando dzakasikwa dzakagadzirwa nehutachiona hwemishonga (izvo zvinowanzoitika zviri zviviri T3 uye T4 ) nokuti ivo vakasiyana nemishonga.
Kuti Uite Chikamu Munjodzi
Kana ukasangana nezvikwereti uye unofarira kubhadharwa kuti ubatanidzwe mune chirongwa ichi chechipatara, taura: Mohamed Shakir, MD, 301-295-5165, mohamed.shakir@med.navy.mil naPatrick Clyde, MD, 301-295- 5165, patrick.clyde@med.navy.mil.The Clinical Trials.gov nhamba yekutsvaga kwekuedzwa iyi NCT01739972.
Iwe unogona kuona zvakazara ClinicalTrials.gov rondedzero.