Vanachiremba Dzimwe Nguva Kuverenga Anticonvulsants for Pain Management
Kana iwe uri kutambura nemamwe marudzi ekurwadziwa kusingaperi , unogona kushamisika kuziva kuti mishonga inopesana nekugunun'una inogona kubatsira kubvisa marwadzo ako.
Anticonvulsants, kana anti-seizure mishonga, inoshanda seanorganics adjuvant . Izvozvo zvinoreva kuti vanogona kubata mamwe marudzi ekurwadziwa kusingaperi kunyange zvazvo vasina kugadzirirwa chinangwa ichocho.
Kunyange zvazvo kushandiswa kukuru kwemishonga inopesana nekutengesa kunodzivirira kukanganisa, anticonvulsants inoita seinobudirira pakurapa mamwe marudzi ekurwadziwa kusingaperi.
Izvi zvinosanganisira marwadzo europathic , akadai seuroperial neuropathy, uye misoro isingagumi , yakadai semigraines.
Ko Mishonga Inorwisa Misiki Inobatsira Maviri Asingaperi Here?
Zvidzidzo zviri kuitwa pamusoro pekubudirira kwemishonga inopesana nekugunun'una kwekutambudzika kusingaperi.
Zvimwe zvidzidzo zvakaratidza kuti mamwe maitiro emishonga ekurwadziwa anorwadza anofanirwa kuongororwa musati mishonga inorwisa-seizure inorayirwa kurwara kusingaperi , apo vamwe vanoti anticonvulsants ndeyekurapa kwekurapa uye anowanzova nemigumisiro yakareba kwenguva refu.
Mishonga mashomanana inopesana nekutengesa mishonga ndeye FDA inogamuchirwa kwehutano husingaperi, kusanganisira carbamazepine (ye trigeminal neuralgia ) uye gabapentin (nokuda kweperigia neuralgia , kana shingles kurwadziwa).
Kushandiswa kwemishonga inorwisa-kugadzirisa kune mamwe marudzi ekurwadziwa kusingaperi kunofungidzirwa se "off-label use," sekunge pane zvidzidzo zvishomanana kuti zviongorore kubudirira kwavo munguva refu yekushungurudza kurwadziwa kwenguva refu.
Kazhinji Inoshandiswa Mishonga Inoshandiswa Kuzvidzivirira Kwechirwere Chisingaperi
Heano mamwe emishonga inorwisa-seizure iyo inowanzoshandiswa pakuchengeta kurwadziwa:
Gabapentin (Neurontin) . Gabapentin inogamuchirwa kuitira kurapwa kwemazuva anotevera postherpic neuralgia. Inobatsirawo pakurapa chirwere cheshuga cheuropathy.
Carbamazepine (Tegretol) .
Carbamazepine yakanga iri tsika yekurapa-anti-seizure mishonga yemarwadzo europathic, kunyanya pakurapa kwechiremera chemauralgia (iyo iyo FDA inogamuchirwa). Inobatsirawo kune chirwere cheshuga chirwere chepurovhesi uye postherpic neuralgia.
Pregabalin (Lyrica) . Pregabalin mushonga mutsva unorwisa kugunun'una hunoshandiswa mukurwadziwa kusingaperi, kunyanya kurwadziwa kunosangana ne postherpic neuralgia uye chirwere cheshuga chirwere chepfungwa.
Tiagabine (Gabitril) . Tiagabine is anti-seizure mishonga inoshandiswa muhutano hweuropathy hunobatanidza nenyunje yekukuvadza, zvakadai sekurwadziwa kwemuviri .
Topiramate (Topomax) . Topiramate is anti-seizure mishonga inowanzoshandiswa seprophylactic migraine treatment. Prophylactics inotorwa kuti itadzivise marwadzo panzvimbo pokuridzora kana ikatanga.
Valproic Acid (Depakote) . Valproic acid inonzi anti-seizure mishonga inoshandiswa pakurwadziwa kwemigraine uye inogona kushanda pakurapa mamwe mhando dzemarwadzo emutsipa.
Lamotrigene (Lamictal) . Lamotrigene inogona kushandiswa kurapa marwadzo anokonzerwa neutatu hwemauralgia neuralgia syndromes, kana marwadzo ane chirwere chepfungwa.
Mimwe Mishonga inorwisa Anti-Seizure uye Upenyu Husingaperi
Nemhaka yenzira iyo vanoshanda nayo purogiramu yemagetsi, mishonga inotevera inorwisa kugunura inogonawo kubatsira mukurapa kurwadziwa kusingaperi.
Kubudirira kwavo muhutano husingaperi huripo, zvisinei, hauna kuongororwa zvakakwana:
- Phenytoin
- Phenobarbitol
- Clonazepam
- Oxcarbazepine
- Zonisamide
- Levetiracetam
Zvichida Zvimwe Maitiro
Mishonga yekurwisa-gwapa ine zvishoma madhara kana ichienzaniswa nedzimwewo kushandisa kwenguva refu kushandiswa kwemishonga, kunyange zvishomanana zvakakodzera kutaurirwa.
Iyo mikuru mikuru inosanganisira:
- kugona
- chizoro
- kuneta
Mishonga yekurwisa-gwagwa inogonawo kukonzera zvinotevera migumisiro:
- kuvimbiswa
- nausea
- kuvhiringidzika kana kunetseka kuisa pfungwa
- kurasikirwa nekuenzanisa kana dambudziko nekubatana
- zviratidzo zviviri
- slurred speech
- rashes
- kurasikirwa nechido
- dry mouth
Yeuka: Mishonga inobata munhu wese zvakasiyana. Zvaunowana zvichave zvakasiyana. Kana uchinetseka nezvekutora mishonga yekurwisa mishonga yekurwadziwa kusingaperi, taura nemupiki wako wehutano nokukurumidza nokukurumidza.
Sources:
American Chronic Pain Association. APCA Mishonga uye Upenyu Husingaperi: Kuwedzera 2007 .
Tremont-Lukats, IW, Megeff, C., uye Backonja, MM Anticonvulsants for Syndromes Neuropathic Pain Syndromes: Nzira dzekuita uye nzvimbo muTrans. Zvinodhaka. 2000 Nov; 60 (5): 1029-52.
Wiffen, PJ, Collins, S., McQuay, HJ, et al. Anticonvulsant Zvinodhaka zveAkare uye Zvisina Kurwara. Cochrane Database yekuongorora kwakarongeka 2005, Nyaya 2.