Chii Chinoita Kuti Tatu Isina Kusiyana Neimwe Mimwe Makondombera Epabonde?
Overview
Kuonekwa kuti une kenza yemazamu inguva inotyisa; kuongororwa kuti ane kenza kanhatu inoratidzira mucheche (TNBC) inowedzera mutoro. Parizvino yakashandiswa kunorapwa, yakatorwa kwemakore mashanu kusvika ku10 zvichienderana nekuguma kwekushanda kwakasimba kuderedza dambudziko rekudzoka, haisi kubudirira semushonga weTBC. Kunyange zvazvo vatsvakurudzi vari kushanda kuti vawane rubatsiro rwakarongwa ruchabatsira kuderedza dambudziko rekudzoka kune avo vanoonekwa neTBBC, imwe haisipo panguva ino.
Zvatinoziva NezveTBC
- Maminitsi makumi matatu nemashanu, mukadzi muUnited States anoonekwa kuti ane katatu yakaipa
- Iko kunowanzova kenza yakanyanya kurwisa
- Zvinonyanya kudzoka uye zvakaoma kuporesa nokuti hapana mazano ekurapa
- Kana zvikaitika, zvinowanzoita kudaro mumakore mashanu okutanga mushure mekushanda kwakasimba.
- Chemotherapy yakaratidza kubudirira kwemishonga kune kanhatu dzakaipa dzemazamu dzemazamu.
Iyo INBC Inofananidzwa Sei Nemamwe Makondombera eBerechi
Kenza yemazamu haisi chirwere chimwe chete. Chaizvoizvo, izwi rechirwere chemucheche rinomirira mhando dzakawanda uye zvinyorwa zvekenza zvinowanikwa muzamu; ivo vanoongororwa nekuti kana kwete ivo vane mapepa anopa mafuta akawanda emukenza. Izvi zvinogamuchirwa zvinosanganisira isrogen receptor, kana ER; progesterone receptor , kana PR uye munhu epidermal growth factor receptor 2, kana HER2
Apo izvi zvinogamuchirwa zviripo, zvinobatsira boka rekurapa kenza yemukati sarudzo yakanakisisa yekurapa rudzi rwakasiyana rwekenza.
Eriya chirwere chepamuti chepamuviri, chirwere chemukati chemukondombera uye chirwere cheHER2 chakanaka chepamuviri, kurapwa kunosanganisira mishonga inodzivirira, inonoka kana kumisa kenza yemukera nekutsvaga izvo zvinogamuchirwa. Iyi mishonga inopiwa pashure pekuguma kwekushanda, iyo inosanganisira kuvhiyiwa, chemotherapy uye / kana remishonga inonzi radiation.
Zvinodhaka zvakadai se tamoxifen , uye aromatase inhibitors , zvinotarirwa neestrogen receptor, chinangwa chinodhaka cheHER2 ndicho Herceptin.
Triple negative isha yekenza subtype iyo haina chero yezvinhu zvitatu zvinogamuchirwa, izvo zvinoshandiswa sezvinangwa zvekurapa kenza. Zita rayo rinouya kubva pane kuti hazvina kunaka kweEER, PR, uye HER2 receptors. Nemhaka yokuti nhatu dzisina kunaka hadzina chero ipi zvayo idzi, mutsara uyu wekenza yemazamu haagamuchiri tamoxifen uye Herceptin.
Inenge makumi manomwe kubva muzana yekamuti yemazamu iE ER positive; 15 muzana yekamuti yekenza ndeyeHER2 yakanaka, uye 15 muzana yekenza yemazamu inowedzera katatu.
Kurapa
TNBC inowanzotarisirwa nekubatanidzwa kwekuvhiyiwa inoteverwa nemirairo uye / kana chemotherapy. Zvokuvhiya zvinoshandiswa zvakafanana nezvimwe zvekenza zvepabonde. Lumpectomy pamwe nekurasikirwa kwemaawa kunogona kuva sarudzo inobva paukuru uye nzvimbo yechiremera.
Zvimwe zvinhu zvinogona kuita kuti mastectomi isarudze kusarudzwa kwepamusoro kana kuti isina kuberekwa patsva. Kana mukadzi ane chirwere chikuru, zvinogona kutarisirwa nekemotherapy musati mavhiyiwa. Chemotherapy, inowanzopiwa chirwere chinotevera, inoramba ichiva mushonga unoshanda zvikuru kune vazhinji veNBC.
TNBC New Treatment Research
Izvo zvinoramba zvichiri kuenderera mberi kutsvakurudza kutsvaga mushonga mutsva. Mukukurukurirana naDr. Marc Hurlbert, Chief Mission Officer , weBast Cancer Research Foundation akati, "IBCRF yekuongorora mishonga mune mushonga mutsva inosanganisira zvidzidzo zvakasiyana-siyana zvekurapwa kweTBBC itsva. Chimwe chidzidzo chakadai chinosanganisira kuongorora PARP inhibitors muzvibatanidzi nemimwe mishonga muTBC. "
Risk Factors
Dambudziko rechitatu rinogona kuitika kune vakadzi vezera ripi neripi, dzinza uye dzinza. Izvozvo, zvisinei, zvinowanzoitika nguva zhinji muAfrica neAfrica-vakadzi veAmerica, pamwe chete neveCaribbean neAsia vanomudzimai vanotanga-menopausal, uyewo kune vakadzi vane mutsauko we BRCA.
Kudzivirira
Mune shoko, kwete, katatu zvakaipa haigone kudziviswa. Panguva ino, hapana kenza yemazamu inogona kudziviswa. Kune zvinhu zvinogona kuitwa kuderedza dambudziko rekuwana kenza yemvere, yakadai sokuchengetedza uremu hutano, kurarama nguva dzose, kutevera kudya kwezvirimwa, tarisa shuga yekudya, kuchengetedza doro kushandiswa kusvika padziviri uye usapinda mafuta akazara.
Kunyangwe kana uchichengetedza mararamiro ane hutano, chinhu chakanaka iwe unogona kuzviitira iwe pachako ndechekuona kusangana kwekutanga, izvo zvinogona kuita kuti uwane kenza yemazamu panguva yekutanga kana zviri nyore kubata.
Ziva nhoroondo yemhuri yako yekenza yemazamu, kurukura nayo nachiremba wako kana gynecologist uye, kana pane kenza yepamuviri mumhuri, tevera mazano echiremba wekuongorora.
Kubvira pa85 kubva muzana yehutachiwana hwemucheche hunoitika kune vakadzi vasina ruzivo rwechirwere chechirwere, iyo pfungwa yakanaka kutanga kutarisa pazera remakore makumi mana. Pasinei nekuchinja kwechangobva kuitika pamusoro penguva yekuwana mammogram yako ekutanga nekuronga mammograms anotevera mushure meizvozvo, ziva kuti mammograms uye kuongorora mazamu ezvokudya zvinotora chikamu chinokosha pakuziva kare.
Izwi Fron
Kana iwe ukaonekwa kuti une kenza katatu isina kushaya mukomana, unoda kutsvaga kurapwa kubva kune vanachiremba vanonyanya kugadziriswa nekenza yemazamu uye vanogara vachibata vakadzi vanove vakaonekwa kuti vane kenza katatu isina mucheche. Mazamu ako anoda kuongororwa zvakakwana uye iwe unoda kuziva zvose zvekurapa kwako usati watanga kurapwa. Kana iwe uri pasi pemakore makumi matanhatu, chirwere chako chezvekurapa chichada kuti iwe uwane mazita ekuongorora mazita kuti uone kana iwe uri BRCA mutation carrier, sezvimwe zvirwere zvingave zvakakunakira iwe.
Zvakakosha kuti mumwe munhu aende newe kuti asangane nechiremba wako chiremba uye wako oncologist uye chero umwe mupi wehutano. Kushanda senzeve mbiri dzechipiri, munhu uyu anoda kunyora tsanangudzo dzakakwana yezvakaitwa nachiremba pamusoro pezvinhu zvitatu zvakaipa; nzira dzako dzokurapa uye nei izvi zviri izvo zvaunogona. Pakutanga, kuipa katatu kunogona kuva kwakaoma kunzwisisa, kunyanya kupa dambudziko rako. Iwe unofara kuva nemashoko ekudzokorora mushure memusangano wega wega.
Usanetseka kubvunza mibvunzo yakawanda yeboka rako rekurapa sezvo zvinotora iwe kuti unzwisise hurongwa hwako hwokurapa. Wana maonero echipiri kubva kune mumwe chiremba ane ruzivo rwakawanda mukurapa varwere vane kenza katatu isina mucheche.
Dzokera kumasangano ane ruzivo, mapurogiramu, uye masangano ekutsigira avo vanotambura katatu zvakaipa, zvakadai se:
- Kurarama Kunze Kwechirwere Chepabonde
- Chirwere cheTatu chisina kunaka cheCcercer Foundation
- CancerCare
> Sources:
> America Cancer Society. Ndeipi Breast Cancer Classified?
> BREASTCANCERORG Nhatu dzisina kunyanya kuwanikwa nekenza kenza.
> National Cancer Foundation. Chii chinonzi Triple Negative Breast Cancer?