Kurasikirwa kweropa rega rega kunobatana zvikuru nehutachiona
Lymphopenia (inozivikanwawo se lymphocytopenia) ishoko rinoshandiswa kurondedzera nyika umo iwe hauna imwe rudzi rweropa rinonzi lymphocyte. Lymphocytes ndeimwe yemhando mitatu yeropa rega rega (rinozivikanwa se leukocytes) rinowanikwa muropa. Leukocytes inoshanda sechikamu chemuviri wedu wekutanga mishonga yekudzivirirwa nekudzivirira zvirwere-zvinokonzera zvirwere zvakadai sebhakitiriya, mavairasi, uye zvirwere.
Lymphopenia inowanzokonzerwa nehutachiona, kusanganisira firima yakawanda, uye inowanzodzoka pachayo pakarepo chirwere chacho chave chacheneswa. Mumamiriro ezvinhu apo chinokonzera idiopathic (chekusingazivikanwi kwakabva), zvinogona kuratidza kuti chinetso chakanyanya kuoma.
Kunzwisisa Lymphocytes uye Lymphopenia
Mazhinji emasero muropa redu ndiwo erythrocytes (masero matsvuku eropa) ayo anotakura kutakura okisijeni mumuviri wose. Izvi zvinoteverwa ne thrombocytes (platelets) uye leukocytes.
Leukocyte inobudiswa mumapfupa emapfupa uye inopararira pachena muropa rega senhengo yezvirwere zvekuzvidzivirira. Lymphocytes inomirira chikamu chikuru chemasero aya, kubva chero kupi zvako kubva pa25 ne45 muzana.
Lymphocytes inogona kuve yakaputsika muzvikamu zvitatu:
- Muurayi wepanyama (NK) masero anoshanda seyokutanga yezvidziviriro zvemuviri wezvirwere
- T-masero anobudiswa mukupindura kune pathogen chaiyo
- B-masero anobudisa zvirwere zvinoshandiswa zvinobatsira mamwe masero kuziva uye kupedza zvirwere
Sezvo zvakadaro, lymphopenia inogona kuonekwa nemhando ye lymphocyte inobatwa. Semuenzaniso, HIV inonyanya kukonzera CD4 T-cells kuti iwane utachiona, zvichiita kuti kurasikirwa kukuru kweiyo ikero. Kurasikirwa kweB-seli kunowanzobatanidzwa nemishonga yekudzivirira-immressive (yakadai inoshandiswa kune vagashiri vechirungu) apo NK kudzvinyirira inowanzosawanzoitika.
Zvinokonzera Lymphopenia
Lymphopenia inogona kukonzerwa nemamiriro ezvinhu akawanda, kusanganisira kutapurika uye kushandiswa kwemishonga. Dzimwe nguva, mamiriro acho angangobatsira chete lymphocytes. Mune vamwe, zvinogona kuva mugumisiro wekuderera kwemasero ose eropa.
Somuenzaniso, apo kurapa kwehutachiona hwehutachipatitis kunosanganisira peginterferon uye ribavirin, inogona kukonzera kudzvinyirira kweeutrophils (neutropenia) kana kungoita lymphocyte (lymphopenia) kune vamwe vanhu. Mune vamwe, zvinogona kukanganisa yose yakachena yemasero eropa (leukopenia).
Lymphopenia inowanzobatanidzwa nemamiriro ezvinhu anokanganisa marora emapfupa, kusanganisira:
- Zvirwere zvepachirwere zvinokanganisa pfupa marora basa
- Kukanganiswa kweKonenital kunosanganisira kupera kwemafupa emabasa
- Kanzira kana zvimwe zvirwere zvinokanganisa fufupa
- Zvirwere zvinokonzerwa nehutachiona zvinoparadza masero emachena eropa kana mapfupa emasero masero
- Zvirwere zvakanyanya zvinouraya masero machena eropa nokukurumidza kudarika zvazvinogona kubudiswa
- Mishonga, yakadai semishonga inorwisa mabhakitiriya, iyo inogona kuparadza masero machena eropa
Zvirwere kana Mamiriro Akafanana neLymphopenia
Zvirwere uye mamiriro ezvinhu anowanzobatanidzwa ne lymphopenia zvinogona kurondedzerwa zvakanyanya sekuve pathogenic (yakabatana nehutachiwana), cytotoxic (toxic to cells), congenital (inokonzerwa neine genetic defect), kana chikafu.
Dzinosanganisira:
- Aplastic anemia (iyo isingawanzoitiki apo muviri unorega kubudisa masero eropa)
- Chemotherapy
- HIV
- Hypersplenism (kuparadzwa kusati kwasvika kwemasero eropa nepleen)
- Leukemia (rudzi rwekenza yeropa)
- Lupus (an autoimmune disorder)
- Kusagadzikana kwezvokudya uye vitamini zvakashata
- Myelodysplastic syndromes (boka rematambudziko rinokanganisa kubudiswa kwemasero eropa)
- Rheumatoid arthritis (imwe chirwere chega selfimmune)
- Radiation therapy
- Tuberculosis
Ndeipi Mhepo Yakachena Yemazi Yeropa Inotitaurira
A low white white cell count inowanzoonekwa apo chiremba wako anorayira nezvechimiro chauri kutarisana nacho.
A low count is rarely finding unticipated.
Mune zvimwe zviitiko, rudzi rwechichena chemuviri weropa runokanganisa runogona kukwana kukutsanangurira kune chinangwa chekuongorora. Pane dzimwe nguva, iwe unogona kuwedzerwa kuongororwa kwechimwe chinhu kuti ubatanidze pamwe chete chikonzero.
Rimwe rakanyanya pasi rakachena rekuyera ropa rinoita kuti iwe uwane dambudziko guru rekutapukirwa. Kana izvi zvichiitika, iwe unogona kutora matanho chaiwo ekudzivirira chirwere. Izvi zvinosanganisira kudzivisa vamwe vanogona kurwara, kushambidza maoko enyu nguva dzose uye zvakakwana, kana kutopfekedza chimiro chemaziso kana uri munzvimbo yakachengetedzwa (yakadai sesimbi) nevamwe.
> Source
- > Janeway, C .; Travers, P .; Walport, M ;; et al. Immunobiology (5th ed.) New York neLondon: Garland Science; ISBN 0-8153-4102-6.
- > Regent, A .; Autran, B ;; Carcelain, G ;; et al. "Idiopathic CD4 lymphocytopenia: kliniki uye immunologic maitiro uye kuteverwa kwevatano makumi mana." Mishonga. 2014; 93 (2): 61-72.