Kuputika kwezvirwere kunogona kuwedzera njodzi yehutachiona
Herpes simplex chirwere (HSV) chikonzero chinowanzokonzera chirwere chepachironda chechirwere mumasimba maviri evanhu vane simba rekudzivirira muviri uye avo vanogona kudzivirira zvirwere. Utachiona hunogona kukonzera HSV rudzi rwekutanga 1 (HSV-1) kana HSV rudzi rwechipiri (HSV-2), uye aripo semuromo herpes (akaya mazonda anotonhora kana blister fever ) kana kuti genital herpes (inowanzonzi herpes ).
HSV inonyanya kuparadzirwa nekubatana zvakananga neshungu yakajeka kana muviri wemvura wemunhu ane utachiona, kunyange zvazvo hutachiona hunogona kuitika kunyange kana pasina zviratidzo zvinoratidzika.
Zvidziviriro zvekudzivirira mumhando yemakondomu kana madhenari emeno anogona kuderedza ngozi yekuparidzirwa; zvisinei, hutachiona hunogona kuitika kune dzimwe nhengo dzomuviri kwete nyore kuvharwa nekondomu.
Nhasi, genital herpes ndeimwe yezvirwere zvinowanzobatwa nepabonde, uye inofungidzirwa kuti 775 000 zvirwere zvitsva muUnited States gore negore. Pakati idzi, 80% havazive kuti vane HIV.
HSV Kupindwa uye Zviratidzo
HSV-1 inowanzowanikwa panguva yehuduku uye yaive yakagara ichibatanidzwa nemuromo herpes, asi HSV-2 inotapurirwa zvepabonde uye inonyanya kukanganisa nzvimbo ye anogenital pakati peanus uye marudzi. Zvisinei, mumakumi emakore achangopfuura, zvose zvirwere zvemupombwe neHSV-2 uye hutachiona hweHIV-1 zvakave zvakajairika, zvichida nekuda kwemuromo-zvepabonde zvepabonde. Muzvokwadi, zvidzidzo zvino zvinoratidza kuti kubva kune 32% kusvika 47% yemarital genital inokonzerwa neHSV-1 .
Vanhu vakawanda vanotapukirwa neHSV havana zviratidzo kana zviratidzo zvishoma izvo zvisingaonekwi.
Apo zviratidzo zvinowanzoonekwa, pakutanga zvinouya nekutinhira uye / kana kubwinya, zvakateverwa nemaperembudzi-semakumbo anokonzerwa nokukurumidza kuzaruka, maronda anochema. Mavanga acho kazhinji anorwadza uye anokwanisa kuendeswa nefivhiri uye kuvhupa kwema-lymph glands.
Oral herpes inowanzopa mumuromo uye dzimwe nguva pamucheka wemasumbu.
Genital herpes ndiyo inowanzozivikanwa peni, mukati, gumbo, mabheti, uye anus yevarume, asi zvipembenene zvinowanzoonekwa pane clitoris, pubis, vulva, mabheji, uye anus yevakadzi.
Zvose muromo uye marital herpes zvinotenderera pakati pezviitiko zvezvirwere zvinoshanda, izvo zvinogona kubva pamazuva maviri kusvika kumavhiki matatu, zvichiteverwa nenguva yekuregererwa. Mushure mokunge utachiona hwekutanga, mavairusi anozvibatanidza kune masero emagetsi, apo vanogara kweupenyu hwose. HSV inogona kugadzirisa zvakare chero nguva (uye sechigumisiro chepi zvingangodaro zvinogona kuita kuti zviitike ), kunyange zvazvo kuwandisa uye kuoma kwezvipuka zvinowanzopedza nguva.
Kuongororwa kunowanzoitwa nekliniki yekuongororwa kwemurwere, kunyange zvazvo marital herpes inowanzoomerwa kuongororwa sezviratidzo zvinogona kuva zvinyoro uye zvinongonzwisisika zvimwe zviitiko (zvakadai sewererethritis kana chirwere chetachiona). Kuongororwa kwebhizinesi dzimwe nguva kunoshandiswa kugadzira tsanangudzo yekujekesa, kusanganisira chizvarwa chitsva cheHSV antibody chinogona kuziva HSV-1 kana HSV-2 nepamusoro pe 98% chaiyo.
The Link Between HSV neHIV
Muvanhu vane hutachiwana, sezvinoitwa nevaya vane HIV, nguva zhinji uye zviratidzo zveHSV zvinoputika dzimwe nguva zvingava zvakanyanya, zvichipararira kubva mumuromo kana mazita ekudzivirira kusvika kumadziviri akadzika mumapapu kana muuropi.
Sezvo zvakadaro, HSV yakarongerwa se "AIDS-defining condition" kune vanhu vane HIV kana vakagara nguva yakareba kupfuura mwedzi kana kupa mapapu, bronchi kana sophagus.
Kune humwe humwe huchapupu hunowedzera kuti kutapurirwa kweHIV kunonyatsobatanidzwa neHSV-2. Tsvakurudzo yemazuva ano inoratidza kuti hutachiona hweHSV-2 hunoshingaira, kana hunoita zviratidzo kana kuti husingaenzaniswi, hunoita kuti kuwedzerwa kusununguka kweHIV kubva mumuvirial tishu mune imwe nzira inonzi " kubuda kwemhepo ." Somugumisiro wokudururwa kwakadaro, vanhu vane unhu husingaoneki hwehutachiwana hweHIV vanogona, chaizvoizvo, vane maitiro ehutachiwana anoonekwa mumagetsi ekudzivirira.
Kunyange zvazvo kushandiswa kwekubatanidza antiretroviral therapy (chirwere) ichizivikanwa kuderedza chiitiko chezviratidzo zveHSV , hazvirevi kuti kuderedza HIV inodonha.
Somugumisiro, vanhu vane HIV vane hutachiwana HSV-2 hutachiona hutatu kana kane huwandu huwandu hwekutapurira HIV kune mumwe wepabonde.
Saizvozvowo, vanhu vasina hutachiona hweHIV vane hutachiona hweHSV-2 vari kuwedzera mungozi yekuwana HIV. Izvi hazvirevi chete nokuti maronda akazaruka anopa kuwanika nyore kweHIV, asi nokuti HIV inosungirirana macrophages inowanikwa mukufungidzirwa panzvimbo dzehutachiona hwehutachiona. Mukuita kudaro, HIV inokwanisa kubudirira kuburikidza nemukati mucosal wevakadzi kana anus zvakananga muropa.
Kuchivirira uye Kudzivirira
Parizvino hapana mushonga weHSV-1 kana HSV-2.
Mishonga yemishonga inogona kushandiswa kurapa HSV, kazhinji inoda madhigiri akakwirira kuvanhu vane HIV. Mishonga iyi inogona kugadziriswa mukati-kati (pautachiona hwekutanga kana panguva yekuruka-ups) kana sekuenderera mberi, kurapa kunopisa kune avo vanowanzobuda.
Aya matatu antivirals anowanzoshandiswa kubata HSV ndeye Zovirax (acyclovir) , Valtrex (valacyclovir), uye Famvir (famciclovir). Izvi zvinoshandiswa mumhando yemapiritsi, kunyange maitiro akaoma angaporerwa neyemukati acyclovir. Zvizhinji zvinokonzerwa nezvinodhaka zvinotorwa sezvinyoro, zvine musoro, chirwere, chirwere, uye muviri aches iri pakati pezvinowanzozivikanwa.
Kuderedza hutachiona hweHSV kunogona kuderedza ngozi yekutapurirwa kweHSV nemamwe 50%, kunyanya kushandiswa kwekondomu kusingagumi. Kunyange zvazvo chirwere chinopisa chinenge chichiratidzwa kuti chinoderedza ngozi yeHIV, kumwe kuongorora kwakaratidza kuti kushandiswa kwezuva nezuva kwemukanwa acyclovir kunobatanidzwa nechezasi yehutachiwana hwehutachiona uye kutarisa kwepasi kwezvirwere zvepabonde.
Kuti udzikise njodzi yekuwana kana kutumira HIV kana uine HSV:
- Shandisa makondomu panguva yepabonde, anal anonyadzisira
- Deredza nhamba yako yevakomana nevarume
- Rega zvepabonde panguva yehepe inopuka
- Edzai nguva dzose neHIV uye dzimwe zvirwere zvepabonde
Sources:
US Centers for Disease Control and Prevention (CDC). "Genital Herpes - CDC Fact Sheet." Atlanta, Georgia; yakasvika musi waMarch 26, 2014.
Wald, A. "Genital HSV Zvirwere." Zvirwere zvepabonde. June 2006; 82 (3): 189-190.
Peña, K.; Adelson, M ;; Modhekai, E .; et al. "Genital Herpes Simplex Virus Rudzi rwe1 muvakadzi: Kuongorora muCervicovaginal Specimens kubva kuGynecological Practices muUnited States." Nyaya yeCliniki Microbiology. January 2010; 48 (1): 150-153.
Corey, L .; Wald, A .; Celum, C .; et al. "Migumisiro yevirous-simplex virus-2 pamusoro peHIV-1 kutenga uye kutapurirwa: kuongororwa kwezvirwere zviviri zvinoputika." Zvinyorwa zveAkawana Immune Defence Syndromes. April 2004; 35 (5): 435-45.
Grey, R .; Wawer, M .; Brookmeyer, R .; et al. "Zvichida kutapurirwa kweHIV-1 kuburikidza nehutano hwehutano hwehutano hwehutano hwehutano hwehutano hwehutano hwehutachiwana hwehutachiwana hweHIV-1-hukama huri muRakai, Uganda." Lancet. April 2001; 357 (9263): 1149-1153.
Corey, L .; Wald, A .; Patel, R .; al. "Rimwe zuva-valacyclovir zuva rega rega kuti kuderedze njodzi yekutapurirwa kwemazino emukadzi." New England Journal of Medicine. January 2004; 350 (1): 11-20.
Celum, C .; Wald, A .; Lingappa, J .; et al. "Acyclovir uye kutapurirwa kweHIV-1 kubva kuvanhu vane utachiona hweHIV-1 neHSV-2." New England Journal of Medicine. February 4, 2010; 362 (5): 427-39.