Kana iwe usingazivi nehutachiona hwakarongedzwa, hezvino kurira kwechimbichimbi. Zvakaomeswa (zvakaomeswa) thyroid inonzi thyroid hormone inoshandiswa mushonga inogadzirwa kubva muhutachiona kubva kune nguruve, inozivikanwawo se "porcine thyroid." Mamwe mazita mazita anosanganisira Armor Thyroid , Nature-thyroid, uye WP Thyroid.
Kurondedzerwa kwehutano ndiyo mushonga wemishonga, uye inotungamirirwa neDFA.
Yakange iri pamusika uye yakashandiswa zvakachengetedza kwemakore anopfuura zana.
Kusvikira synthetic thyroxine (inozivikanwawo zvikuru se levothyroxine, ine mazita emagetsi anosanganisira Synthroid, Levoxyl, uye Tirosint) yakatangwa muma1950, chirwere chetachiona chakange chiri chetachiona chetrojoni rinotsiviwa nemishonga.
Apo chigadzirwa che thyroxine chakatangwa, pakanga paine mufaro mukuru pamusoro pekushandurwa kwemazuva ano, zvichienzaniswa nehutachiona hwakarongedzwa, hwaionekwa sehwekare. Panguva iyoyo, vanachiremba vazhinji vakashandura varwere kune iyo yekugadzira mishonga uye havana kutarisa shure. Munguva iyi, maitiro ehutachiona-ayo anonzi Synthroid-akazova chekubhadhara kune makambani akasiyana-siyana emishonga akave ane kodzero dzeStroroid pamusoro pemakore, ayo akabatanidza Bhoots, BASF, uye iye zvino AbbVie, tsvina yeAbbott Labs.
Zvose pamwe chete, kufanana nemakambani makuru ezvinodhaka, vanogadzira Synthroid vakatsigira misangano yezvokurapa, kuputika kwegorofu, mhirizhonga, ruzivo rwekutsvakurudza, uye mari yevatauri, uye vakapa mabhuku ehurwere pasina ruzha, mapeni, mapadhi, makg, nezvimwe zvinhu zvinopa zvipo uye kutengesa zvinhu .
Isu tine zvizvarwa zvakasiyana-siyana zvechiremba vakange vakadzidziswa kuchikoro chechiremba kuti vanzwisise kuti maitiro evevothyroxine ndiyo chete inogamuchirwa yehutano mishonga yemishonga, uye vazhinji vanoziva zita rezita rinonzi Synthroid zvakananga, nekuda kwekuwedzera mazita ekudhinda.
Vanachiremba vazhinji havazive kuti utachiona hunenge huripo huripo huripo, kana kuti hunogona kushandiswa zvakanaka kuchengetedza vamwe vane hypothyroid.
Vamwe vanodavira kuti kuisa chirwere chetachiona chakakosha kwakaoma. Aya mazano nengozi anosimbiswa nemafungiro asina kunaka kubva kuvevothyroxine vatengesi vekutengesa, runyerekupe rurefu rwakaratidza kuti utachiona huri kubva pamusika , uye mamwe mashoko anecdotal.
Pasinei nechinangwa chekugadzira levothyroxine, kubvira kuma1990, utachiona hwemasikirwo ehupenyu hwakatanga kuchinjazve, sezvo chido chemishonga chaiyo yakawedzera. Panguva iyoyo, varwere vakanga vasinganzwisisi zvakanaka pamishonga yehutano yehutachiona vaivewo vachiwedzera simba uye vanoziva, vanovonga mune chikamu kuInternet. Varwere vakadzidza kuti pane zvingasarudzwa-pakati pavo, zvakarongedzwa nemishonga yehutano yakadai seArmor and Nature-throid.
Ngatinyatsojekesa: Mitsara miviri mamiriyoni gore yakanyorerwa yehutachiona yakarongedzwa, zvichienzaniswa nemitemo inopfuura mamiriyoni makumi matatu egore re levothyroxine. Asi vakavhiringidza varwere vasinganzwisisi zvakanaka ivo vari kuuya kumasese akadai, vachiverenga mabhuku, uye vachitaura kune vamwe varwere. Semugumisiro, ivo vari kuramba vachiwedzera kuziva kuti kune zvimwe zvisarudzo kupfuura levothyroxine, uye , kuti vamwe varwere vanoona zviri nani pamishonga inorapwa yehutano.
Mhedziso yeEntocrinologist pamusoro pezvakasikwa zveTroroid
Kupfuura paWedocrine Nhasi blog, endocrinologist uye osteopath Thomas Repas, DO, FACP, FACE, CDE, vakaita chikamu chechikamu chechitatu pamusoro pe "Utachiona hwakajeka muhutungamiri hwe hypothyroidism," kubva pakuona kwake sechigumo chemagumo.
- Kurondedzerwa neTyroid muHurumende yeHypothyroidism-Chikamu I
- Kurondedzerwa neTroroid muHurumende yeHypothyroidism-Chikamu II
- Desiccated Thyroid mukutungamirira kweHypothyroidism-Chikamu III
Iko kuongorora kunonakidza nokuti kunopa maonero akajeka mune maitiro ekupedzisira kwema endocrinologists anoona zvakasikwa zvakarongwa nemishonga yehutachiona, uye nei chido chekupedzisira chetemokorinology chinowanzopikiswa kushandiswa kwemishonga iyi. (Izvi zviri mukuenzanisa nekuzara, kusanganisira MDs, avo vanowanzofarira kushandisa utachiona hwehutachiona nokuti vanohuwana huri nani kune vamwe varwere vavo.)
Dr Repas anotanga kutaura achiti iye, savezera rake mu endocrinology, haashandisi utachiona hwakakoshwa, nokuti, "Ndinotenda kuti chirwere chetachiona chakashandurwa kare uye hachifaniri kushandiswa zvakare."
Anotaurawo kuti endocrinologists havashandisi nhumbi dzehondo nekuda kwe "mararamiro asingagamuchirwi ekusiyana-siyana batch," izvo zvinowanzokonzera kuchinja kusingagamuchirwi murosiyo-stimulating hormone. " Achicherechedza kuti levothyroxine inewo kusiyanisa kubva kune brand to brand, anoti, "kana tikafunga kusiyana kwakasiyana pakati pezvinhu zvakasiyana-siyana zve levothyroxine kuti zvive zvakakosha mune zvehutano, saka kuchinja kwakakura kukuru mukati mekugadzirwa kwetachiona hakugamuchirwi."
Muchikamu chechitatu, Dr. Repas anoti apo vanhu vazhinji vasingadi kurongedza "kutungamirira nyanzvi yemarapi kuti aite sei chirwere chema cardiopulmonary panguva yekumanikidzwa kwemwoyo ... zvisingaiti vanhu vanonzwisisa havakwanisi kuedza 'kundidzidzisa' nezvetachiona. Anobva ataura kuti chido chekunzwiwa uye kufarira nzira dzezvakasikwa zvinodhurira kufarira kune utachiona hwehutachiona hwakasikwa.
Dr. Repas anoti kupikisa kwake kwehutano hwemhando yehutano hwakavakirwa musayenzi, asi iye pane hove. Dr Repas inokundikana kutaura kuti hakuna maviri-mapofu, mazano-vezera, akaongorora-kaviri-mapofu anoenzanisa levothyroxine kuti ave nehutachiona hwehutano maererano nekubudirira pakugadzirisa zviratidzo zvoutano.
Ichokwadi, Dr. Repas pachake anobvuma, mune chikamu chemashoko cheChikamu I:
Pamusoro pezvinyorwa izvi, kunyanya kunetseka kwandakaitwa nekrisiti (kana levothyroxine kana T3) ndiyo iyo yavakarayira nenzira inoguma kwenguva refu yakareba hyperthyroidism. Kana murwere asiri hyperthyroid uye vari kuita zviri nani pane chimwe chigadzirwa nemumwe, zvakaoma zvikuru kupopotedzana naizvozvo.
Anogumisawo Chikamu chechitatu nehurukuro inoshamisa:
Pakupedzisira, vhiki yapfuura ndakaona mukadzi uyo akanga ava nemakore makumi emakore aine utachiona. Ndakatsanangura kuti isu iye zvino tinosarudza levothyroxine pane kuti tive nehutachiona. Ini ndakakurumidzawo kuratidza kuti hormone yake yehutori-stimulating yakave yakakwana, pakati pe 0.7 mIU / L uye 1.0 mIU / L pamusoro pemakore akawanda apfuura. Akange asina zviratidzo; zvakanga zvakandiomera kuti ndiite nharo nekubudirira. Mushure mekutaurirana uye kumubvunza kuti aida kuitei, akasiya hofisi yangu ichiri pakuchengetedzwa kwetachiona.
Apo nyaya idzi dzakatanga kudhindwa, paiva nemashoko mazhinji akasiyiwa nevarwere vakatsamwiswa navo. Kune rumwe rutivi, Dr. Repas akanga achiedza kutsanangura kuti nei asingatendi muZviyo zveTroroid, achizviti haina zvesayenzi uye achitaura kuti vateveri varo vari kuita "kufunga kwemashiripiti." Asi Dr. Repas haana kupa huchapupu hwezvesayenzi kutsigira zvaanotaura, uye akaregeredza hupenyu hwehupenyu hwemazana nemazana ehutano hwetachiona nevarapi.
Panguva imwecheteyo, Dr Repas anobvumawo, kubva pane maonero anobatsira, kuti kunyanya kunetseka kuri kukonzera murwere kune hyperthyroidism pane chero mushonga wehutachiona-kwete kungofanana nehutachiona. Uyewo anobvuma kuti kana murwere anogona kukwanisa kunyatsogadziriswa paine chirwere chetachiona, saka haaoni chikonzero che "kukakavara nekubudirira."
Dr Repas haizotangi varwere vatsva pavanenge vachitsvaga utachiona-kunyange kana vakakumbira. Kana mumwe murwere aripo on levothyroxine asiri kunzwa zvakanaka anokumbira kuti aende kunzvimbo yakagadziriswa yehutano, haazoiti. Asi kana murwere atove aripo uye achiita zvakanaka, ari kutaura kuti haazo "arwisana nekubudirira" uye acharamba achipa chirwere chetachiona kwaari.
Mune dzimwe nzira, Dr. Repas ane mafungiro akajeka kupfuura mamwe magumo ekupedzisira. Iko kune vamwe vasingazomboni kuva nevarwere paT3 mishonga kana chechiroid. Vamwe vanotopisa varwere vavo vanoomerera pamishonga yehutachiona hwepanyama, kana kuti ndiani asingateereri mazano. Asi Dr Repas inonyatsomiririrawo maonero atinoona pakati pezvemagokorokorikori munharaunda. Chinonyanya kukoshesa ndechekuti "TSH yakarongeka" "uye chirongwa chavo ndechekuita kuti varwere vapinde muhutano hwakanaka. Chiratidzo chechiratidzo chinoratidzika sechisingabatsiri uye chinotora chigaro kumashure kune vatungamiri veTSH mazinga.
Shoko kubva
Kana iwe uri kurapwa nokuda kwe hypothyroidism ne Synthroid kana levothyroxine chete uye iwe uchiri nezviratidzo zvekuramba uri hypothyroidism, taura nachiremba wako pamusoro pekukwanisa kuedza kutaridzika kwechirwere chetachiona.
Kana chiremba wako asingatsvaki kufadza izvozvo zvisingakupei chikonzero chakanakisisa chakanaka kuhutano hwako, zvinogona kushanda zvakanakisisa kufarira kutsvaga imwe pfungwa kubva kune mumwe muongorori- zvakanakira chibatanidza kana kuti chiremba akakurumbira nehuwandu hwakakwana hwe mishonga yemishonga yekirori-inopesana nemagariro ekupedzisira.
> Sources:
> Braverman, L, Cooper D. Werner & Ingbar's The Thyroid, 10th Edition. WLL / Wolters Kluwer; 2012.
> Garber, J, Cobin, R, Gharib, H, et. al. "Clinical Practice Guidelines for Hypothyroidism muVakuru: Cosponsored neAmerican Association of Clinical Endocrinologists uye American Thyroid Association." Endocrine Dzidzira. Vol 18 Nha. 6 November / December 2012.
> Kudya, T. DO, FACP, FACE, CDE. "Kurondedzerwa nehutano muhutungamiri hwe hypothyroidism: Zvikamu I, II, III." Endocrine Nhasi. January 2009. Online