Uyu anoropi anogona kukuisa pangozi yekuvhara ropa
Lupus anticoagulant (LA) is antiphospholipid antibody inowanikwa nevanhu vakawanda vane lupus. Lupus anticoagulant inowedzera kukwanisa kweropa rako kupfeka. Saka, kana iwe une anti-antibody iyi, une dambudziko guru rekutarisa ropa . Iwe haufaniri kuva ne lupus kuti uite LA.
Maererano neJohn Hopkins Lupus Center, antiphospholipid antibodies inorwisana ne:
- Semu membrane zvinonzi phospholipids
- Mimwe mapuroteni eropa anosunga ne phospholipid
- Matambudziko anoumbwa apo mapuroteni uye phospholipid vanosunga
Inenge 50 muzana yevanhu vane lupus vane antiphospholipid antibodies. Antiphospholipid antibodies inopesana nebasa rinowanzoshandiswa nemidziyo yeropa uye rinogona kutapudza kuvhara kwemidziyo yeropa kana kuti ropa. Izvi zvinetso zvinogona kutungamirira kumarwadzo , kurwadza kwemwoyo, uye kupererwa.
Haisi Nguva Yese Yakabatana neLupus
The antiphospholipid antibody lupus anticoagulant yakatanga kuwanikwa mu systemic lupus erythematosus varwere muma1940. Nhasi, vanachiremba vanoziva kuti LA inowanikwawo kune vanhu vane dzimwe zvirwere zvinodzivirira (zvakadai sekuputika kwechirwere chechirwere), zvimwe zvirwere uye maronda, pamwe chete nevanhu vanotora mishonga, kusanganisira phenothiazines, phenytoin, hydralazine, quinine, kana antibiotic amoxicillin .
Zita rokuti lupus anticoagulant iri kutsausa nokuti rinoratidza kuti munhu anoramba achiwedzera ropa.
Muzvokwadi, lupus anticoagulant inobatsira ropa kuvhara. Ichokwadi, inenge 50 muzana ye lupus varwere vane lupus anticoagulant vachawana ropa clot pamusoro pemakore makumi maviri emakore, izvo zvinokonzera kuvapo kweiyo munhu anonzi nengozi.
Kana uine lupus anticoagulant, iwe unofanirwa kunyanya kuziva zviratidzo uye zviratidzo zveropa rinosanganisira:
- Mhete yekudzivirira kana kubwinya
- Kupfupika kwemhepo
- Pain, numbness, uye pallor mune ruoko kana gumbo
Kuedzwa kweLupus Anticoagulant
Coagulation test, iyo inoyera kuti zvinotora nguva yakadii ropa kuvhara, inoshandiswa kuongorora lupus anticoagulant. Vanachiremba vanobata chirwere chemapus kazhinji vanotanga ne coagulation test inonzi inonzi activated partial thromboplastin time (aPTT).
Kana zviitiko zveAPTT zvikaitika, vanachiremba vachashandisa muedzo wakaoma kuti uve nechokwadi. Kazhinji, iyi ndiyo inonzi Modified Russell viper nguva inopisa (RVVT), iyo inoshandisa phospholipid uye uturu kubva kuna Russell nyoka nyoka kuti ione lupus anticoagulant. Zvimwe zvinonzwisisika zvinogadziriswa zvinogona kushandiswa ndezveplatelet neutralization process (PNP) uye kaolin clotting time (KCT).
Kudzivirira Kuvhara Ropa
Vanhu vanoedza kuti vawane ruzivo rweRA vanowanzotaurirwa ropa vanocheka kuti vadzivirire kudzivirira, asi apo chete kusina kushandiswa kwekuvhara kunozviratidza. Steroid inogona kurongerwa kuti ibatsire mukuderedza maitiro evanhu vanorwisa.
Nekodzero yakarurama, zvinetso kubva ku lupus anticoagulant zvinokwanisika.
Pane zvimwe zvinhu zvaunogona kuita kuti urege kudzivirira ropa kana une LA:
- Dzivisa isrogen-based birth birth control mapiritsi nemishonga yehomoni yekurega kuenda kumwedzi
- Usasvuta kana kushandisa zvimwe zvigadzirwa zvefodya
- Usagara kana kurara pasi kwenguva yakareba pane imwe nguva apo iwe wakarara
- Paunofamba, simuka nguva nenguva kuti ropa rako riyerere
- Sungai maziso enyu kumusoro uye pasi apo musingagoni kufamba-famba
Kana iwe uine hanya nezvekuvhara ropa, taura nachiremba wako nezve LA uye iwe pachako panjodzi yekudzidzira ropa. Chiremba wako angave ane mazano, zvakananga kwauri, izvo zvinogona kubatsira kuderedza ngozi yako.
Sources:
Antiphospholipid Antibodies. The Johns Hopkins Lupus Center.
Lupus Anticoagulants uye Antiphospholipid Antibodies. MedlinePlus. US National Library of Medicine. January 20, 2015.
Antiphospholipid Antibodies. Lupus Foundation of America. August 2008.