Kubatana pakati peAm Amyloid Angiopathy uye Stroke
Mamiriro ezvinhu anonzi amyloid angiopathy inowanzobatanidzwa nekurova. Kutenda kweAiloid isiopathy yekuunganidza kweprotein fragments mumidziyo yeropa. Kazhinji, kuvapo kweamyloid muuropi kunobatanidza nechirwere cheAlzheimer, chirwere chePasinson uye marudzi mazhinji ehutano hwemmmentia.
Zvisinei, majoe emamyloid muuropi anogonawo kuchinja mishonga yeropa, zvichiita kuti zvive zvisina kusimba uye zvinogona kubuda ropa.
Izvi zvinokonzera kubuda ropa muuropi, iyo inowanzotumidzwa sechirwere chinopisa kana intracerebral hemorrhage.
Chiratidzo
Zviratidzo zveAngiopathy yeAmyloid inopesana zvichienderana nemishonga yeropa yakabuda ropa uye kuti mishonga yeropa isina simba yakabuda sei. Kana pane zvishoma zvekubuda ropa, pangave pasina zviratidzo zvachose.
Kana zvirwere zvinoramba zvichibuda ropa zvichiitika, zviratidzo zvinogona kutanga kuonekwa. Mune zvimwe zviitiko, zviratidzo zvinogona kunge zvisinganzwisisiki, zvichikonzera kurasikirwa kwekuyeuka kwepfungwa kana kushaya simba muuropi hunoita basa, zvakadai sekusaona. Kana pane nzvimbo huru yekubuda ropa, izvi zvinogona kukonzera zviratidzo zvehutano zvakakura zvinosanganisira hemiparesis, hemiplegia, kurasikirwa kwekuziva, uye kugumburwa.
Risk Factors
Zvimwe zvinokonzera kukwidziridzwa kwema-amyloid angiopathy hazvinyatsonzwisiswi nevechiremba panguva ino. Iyo chete ngozi yakajeka iyo inoratidzika kuva yakakura, sezvinoitwa amyloid deposits inowanzowanika kune vanhu vakura kupfuura 55 kune ivo vaduku.
Ikoko kunoratidzika kuva neshamwari inoberekwa neamyloid angiopathy, asi vanhu vanogona kukudziridza angiopathy yemamlolo isina mhuri yemamiriro ezvinhu.
Zvinokonzera
Zvinyorwa zveAmyloid zvinogona kuwedzera mukati memasvingo emidziyo yeropa muuropi. Izvi zvinotumidzwa se "amyloid angiopathy".
Kuunganidzwa kweamyloid kunogona kukonzera mitsipa yeropa kuti iwedzere kudarika nguva, kusvika pakupedzisira ichiputsa uye ichibuda ropa.
Amyloid yave ichibatanidzwa nekuputika, iyo ndiyo nzira yemuviri yekubata nekukuvara chero kupi zvako kana kutapukirwa. Kuvhiringidzika, kunyanya kusina kufanira kana kuwedzereka kukuru, kunobatanidza nekurohwa.
Kazhinji, kubuda ropa kunokonzerwa neangyopathy ye amyloid yakanyanya kuduku, inokonzera midziyo miduku yeropa. Nzvimbo duku dzekubuda ropa dzinonzi petechial hemorrhages, uye dzine chimiro chechimiro paB Brain CT kana Brain MRI inoongorora.
Chimwe chezviratidzo zveinterrarebral hemorrhage (kubuda ropa muuropi) inokonzerwa neangyopathy ye amyloid, ndeyokuti inowanzoitika munzvimbo dziri pedo nechokumusoro kweuropi, mukupararira kunowanzoti "lobar."
Kutenda kweAiloid kungatungamirirawo kunzvimbo huru dzekubuda ropa muuropi, izvo zvinogona kutyisidzira upenyu.
Kuziva
Nzira yakatendeseka yakashandiswa kuongororwa nenyuchi yemajoi inonzi amyloid ingano yeropa, iyo isiri nzira inoshanda. Uropi hunyengeri inzira yekuvhiya inotakura ngozi yekubuda ropa uye / kana utachiona. Nokudaro, biopsies hazviiti kunze kwekuti zvakanyatsonaka.
Chiremba wako anokwanisa kushandisa fomu yeMRI inonzi "gradient echo" (GRE) kuwana mamwe mazano anogona kubatsira kujekesa kana iwe ungave neangiopathy ye amyloid.
Uyu ndiwo muedzo unobudirira unoona kubuda ropa muuropi. GURU inogona kuziva nzvimbo huru kana duku dzeropa iro rakaitika maawa kana makore asati aedzwa. Chimiro chechimiro chekunyengedzera kwema-amyloid paGER kakawanda kunonzi "cortical cerebral microbleeding."
Mishonga
Kamwe kubuda ropa muuropi kwakaitika, kurapwa kwepracrarebral hemorrhage pamusana peanyopathy ye amyloid haisi yakasiyana nekurapwa kweproracerebral hemorrhage nokuda kweimwe chikonzero.
Kutanga, kana kubuda ropa kunokonzera kuwedzera kwepracrarebral pressure (ICP), kubva mukudzimba kana kuitika kwemazimbe, tende rako rekuchengetwa kwechirwere rinogona kudikanwa kuita chirwere chekukurumidzira kana kushandisa zvimwe zvingagadziriswa kuti ibvise zvinetso.
kubva ku swellimg Timu yako yezvehutano ingakupawo mishonga inopikisa kuitira kuti urege kudzivirira, izvo zvinogona kukonzerwa neropa muuropi.
Shoko Rinobva
Panguva ino, pane zvishoma zvinogona kuitwa kuti ishandure kushandiswa kwemamyroid protein deposition. Kana wakamboonekwa kuti une chirwere ichi, iwe unofanirwa kuchengetedza chirwere cheropa chemazuva ose uye usazvidzivirira ropa, zvakadai sa aspirin kana plavix, sezvo izvi zvinogona kuwedzera njodzi yekubuda ropa muuropi.
> Sources:
> Neuropsychological Migumisiro yeCerebral Amyloid Angiopathy, Schrag M, Kirshner H, Curr Neurol Neurosci Rep. 2016 Aug; 16 (8): 76