Maererano neUnited States Dhipatimendi Rezvekurima, veAmerica vanodya makirogiramu makumi mapfumbamwe nemakumi matanhatu emagetsi emichero yemichero gore rimwe nerimwe, nhamba iyo inogona kuva nehanya navanachiremba nevamasimist. Mukutanga kwema1990, boka rekutsvakurudza muCanada rakawana kusanganisa kwakaipisisa pakati pemiti yemagetsi nemuchero wemwoyo Plendil (felodipine).
Mumakore gumi apfuura, vanachiremba nevasimamese vakadzidza kuti zvinopfuura makumi mashanu zvemishonga uye zvinodarika-zvinodhaka zvinodhaka zvinokanganiswa nemuchero wemagetsi, kusanganisira mamwe emishonga inonyanya kutaurwa.
Urongwa urwu hunosanganisira mishonga yakawanda inoshandiswa kurapa high cholesterol, kukwirira kweropa , kushushikana, kurwadziwa, erectile kudzvinyirira, uye kuora kwemhuka .
Mazambiringa Anogadzirwa Sei Nemvura Inopedza Mishonga?
Masero anotenderera tumukati mako maduku ane enzyme inonzi CYP3A4. Iyi enzyme inobatsira kuputsa mishonga yemishonga. Zvimwe zvinhu mumuchero wemuropefruit zvinodzivisa CYP3A4 saka saka inobvumira mamwe mishonga kupinda muropa rako.
Kuva nemishonga yakawandisa muropa rako kunogona kuguma nemigumisiro yakakomba kana kuderedza zvinodhaka. Semuenzaniso, kana iwe ukatora chimiro (zvakadai seLimpitor) kuti ubatsire kuderedza cholesterol , kuva nezvakawandisa mumuviri wako kunogona kuwedzera ngozi yako yehutachiona hwehutachiona kana kukuvara kwechiropa.
Ndeapi Mishonga Inopindirana Nemafuta Anonzi Grapefruit Juice?
Mishonga yakawanda haifaniri kushamwaridzana nemafuta emuzambiringa. Zvisinei, mazai emichero anove nemigumisiro pamishonga inopfuura 50, kusanganisira mamwe mishonga yekurapa:
- Abnormal moyo rhythm
- Allergies
- Kufunganya
- Nyota neCOPD
- Ropa rinovhara
- BPH ( yakawedzera prostate )
- Cancer
- Kukosora
- Kuora mwoyo
- Kuora mwoyo
- Erectile dysfunction
- Chirwere chemoyo
- High blood pressure
- High cholesterol
- HIV / AIDS
- Hormonal conditions
- Utachiona-hutachiona, bhakitiriya uye fungal
- Pain
Ndingaziva Sei Kana Muchero Wemapuranga Wakachengeteka Kwangu?
Mucherechera jisi haagadziri zvose zvemishonga inoshandiswa kubata mamiriro akataurwa pamusoro apa.
Tarisa nemupi wako wehutano wehutano kana kuti wemhizha kuti uone nezvehutano hwako.
Yese mishonga mitsva inoongororwa kushandiswa kwezvinodhaka , kusanganisira mazambiringa emagetsi asati agamuchirwa neU.S. Food and Drug Administration (FDA). Apo iwe unorayira mishonga mumishumo kana kuti uatora iyo ku pharmacy yako yekune imwe nyika, unofanirwa kugamuchira murwere weruzivo chepaiti, iyo ichakuudza iwe kana mushonga wako unobatwa nemafuta emurape. Mamwe mapetimita anogona kuisawo tsamba yekunyevera pahombodo yako yemishonga. Kana iwe usingazivi, bvunza mhizha.
Chii Chingaitika Kana Ndikaramba Ndichinwa Muchero Wemizambiringa?
Zvakakosha kuziva kuti mazambiringa emuchero nemishonga zvinogona kuva mungozi ine ngozi! Ngozi yako yekukuvadza zvakakomba inobva mukuda kwemajisiro emuti unonwa, makore ako, uye rudzi rwechirwere chemishonga yako. Uyezve, chiyero cheYYP3A4 enzyme mumatumbo chinokera kubva kumunhu kusvika kumunhu.
Vanhu vakuru vakwegura vanonwa mvura yakawanda yemafuta emurape vanowanzova nemigumisiro yemishonga. Uye, mamwe makirasi emishonga, akadai semasitini (anoshandiswa kurapa yakakwirira ye-cholesterol) uye calcium-channel blockers (inoshandiswa kurapa kukwirira kweropa ) inowanzoita zvirwere zvakanyanya kana inotorwa nemafuta emuzambiringa.
Ko Oranges uye Mimwe Zvibereko zveCitrus Zvinopindirana Nezvinodhaka?
Mazaizi, mandimu, uye limes hazviwanzoitiki nemishonga. Zvisinei, tangelos, yakabatana nemichero yemiti yemichero, uye Sevangeni machero inobata iyo enzyme yakafanana nemafuta emuzambiringa. Sevhisi machero inowanzoshandiswa kugadzira marmalade machena, uye saka funga kana ukasarudza ichi kupararira kwechigunwe chako.
Ndingaita Sei Kuti Ndidzivirire Matambudziko Aine Miti Yemazambiringa?
- Usati watanga mushonga mutsva, taura nemupi wako wehutano wehutano uye wemhizimisi pamusoro pekugona kudyidzana kwezvinodhaka.
- Nyatsoverenga murwere weruzivo pepa rakapiwa iwe paresmiti. Kana iwe usingagamuchiri chimwe chete, wozokumbira.
- Chengetedza mavara ekunyevera pahombodo yako yemishonga usati wasiya pirmiti. Kana mazambiringa emuchero asina kutaurwa, bvunza mu pharmist kana iwe uchikwanisa kuinwa zvakachengeteka.
- Nyora mishonga yemishonga yako yese, kusanganisira mishonga yemishonga uye mishonga inodhaka. Dzokororai rondedzero pamwe nevarapi vako vezvehutano uye mushonga wemasvomhu kuti utsvake zvinogona kuitika mumishonga.
Kana pane mukana wekuti mazambiringa emuzambiringa anoshanda pamwe nemishonga yako, iwe ungada kutanga mangwanani ako negirazi remusi wearangi kana jeriberry juice pane.
Zviripo zvakarongedzwa naNaveed Saleh, MD, MS, musi wa4/26/2016. Nyaya yekutanga yakanyorwa nemunyori akasiyana.
Sources
Abrowowicz M. Drug kusangana nemafuta emurapeti. Tsamba Yechirwere Pamishonga Nezvinodhaka uye Therapeutics, 2004; 46: 2-4.
Kane GC, Lipsky JJ. Zvinodhaka-mazambiringa anogadzirwa. Mayo Clin Proc. 2000; 75: 933-942
Saito M, et al. Zvisingabatsiri zvinokonzerwa nemuchero wemucrosi pa pharmacokinetics yemishonga: tsvaga pane zvidzidzo zvenguva pfupi. Drug Saf. 2005; 28: 677-94.