Kuisa Ropa uye Kurwara Kwechirwere Chesero

Ropa tsvuku rekuisira ropa ndiyo yakagara ichimirira mu sickle cell disease (SCD) . Zvakafanana nedzimwe nzira dzokurapa, kuwedzerwa ropa kune njodzi uye zvinobatsira saka zvakakosha kunzwisisa kuti sei kuwedzerwa ropa kwakakurudzirwa iwe kana mudiwa wako neCSD . Ngatimbokurukurai zvimwe zvezvikonzero zvinowanikwa pano.

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Stroke

Iyo yakagadzirirwa kurapwa kwechirwere mu sickle cell chirwere inopinda ropa yeropa rekuisira ropa. Kurapa kwechirwere munharaunda ino kunoda kuwedzerwa kwakadanwa kunonzi kuwedzerwa kuwedzerwa kana erythrocytapresis. Muchiitiko ichi, ropa richabviswa kubva kumurwere kuenda mumashini achaparadzanisa masero matsvuku eropa kubva pamaplatelet, masero emachena eropa, uye plasma. Masero matsvuku eropa acharasikirwa uye zvimwe zvose zvichadzorerwa zvakare uye vachawana mamwe masero matsvuku eropa. Chinangwa chekurapa iyi ndechokuderedza chikamu chegorosi hemoglobin kubva> 95 kubva kune imwe kusvika kune 30%.

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Surgery

Varwere vane SCD vane ngozi yakawanda yokugadzirisa zvinetso zvinosanganisira kushungurudzika uye kurwadziwa kwepachifu. Ngozi yezvinetso izvi zvinogona kuderedzwa nekuwedzerwa kwepasi pevhiki imwe isati yambovhiyiwa. Zvose zvinorayirwa ndezvekuunza hemoglobin kusvika 10 g / dL. Izvi zvinogona kuwanikwa kuburikidza nekuwedzerwa ropa asi vamwe varwere vane hemoglobine yepamusoro yepamusoro vangave vachida kugoverana kuwedzerwa ropa sezvinotaurwa pamusoro apa. Kudiwa kwekuwedzerwa ropa kunotarirwa ne sickle cell severity, baseline hemoglobin, uye nengozi yose yekuvhiyiwa. Vamwe varwere vanorwara zvishoma vanogona kusada kuiswa ropa mushure mekuvhiyiwa. Izvi zvinofanira kuongororwa pamwe nemukwereti wako wekuchengetedza utano.

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Acute Chest Syndrome

Acute chest syndrome ibasa rinoshamisa rinowanika muCSD. Pane zvikonzero zvakasiyana zvechirwere chechirwere chechirwere chinosanganisira zvirwere zvinotapukira zvakadai sepneumonia. Kuchinja kunowanzoshandiswa kana murwere achida oxygen kana kuti hemoglobin iri pasi kudarika. Kuwedzerwa ropa kare kunogona kudzivirira kufambira mberi mune vamwe varwere. Kana acute chifupa chirwere chinova chakakomba, ichida kurapwa kwakakura (ICU) kurapwa, kuwedzerwa kuwedzerwa kunokurudzirwa nezvinangwa zvakafanana sechirwere chakanyanya.

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Nguva Yakanyanya Aplastic Crisis

Chirwere chepamusoro chinoshungurudza chinokonzerwa nehutachiona neparvovirus B19 (chimiro chomunhu, kwete imbwa imwe chete). Parvovirus ndiyo inokonzera utachiona hwehuduku hunonzi Fifth Disease. Parvovirus inodzivirira bone marrow kubva pakuita masero matsvuku eropa kwemazuva manomwe kusvika kune gumi anogona kukonzera chirwere chakanyanya muvanhu vane SCD. Ichi chirwere chinokonzera chirwere chinodarika chinogona kudikanwa kuwedzerwa kusvikira pfuma yemafuta inodzoka. Varwere vane chirwere cheHemoglobin SC kana kuti sickle beta pamwe ne thalassemia hazvifaniri kudikanwa kuwedzerwa ropa rehemoglobin yavo yakakura kupfuura hemoglobin SS.

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Acute Splenic Sequestration

Kugadziriswa kweSplenic chiitiko apo miropa yeropa yakatsvuka yakavharwa mu spleen uye haikwanise kubuda. Izvi zvinowanzoonekwa kune vana vasati vava nemakore mashanu. Iyo spleen inokura muhukuru kubata masero matsvuku eropa uye izvi zvinogona kukonzera chirwere chakanyanya kuora ropa. IV mvura uye kuwedzerwa kunoita sokuti kunokonzera chirwere ichi kusunungura masero matsvuku eropa. Kamwe kana chirwere chinosunungura masero matsvuku eropa, dzinodzokera kumisasa kudzorera hemoglobin kusvika kune imwe nheyo.

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Kudzivirira kweSroke

Muchiremba avo vakatotambura chirwere kana varwere vari pangozi yekurohwa (sezvinoratidzwa pamusoro pekutengesa doppler, TCD), chirongwa chisingaperi chekuisira ropa chinorudzirwa. Mishonga yekuongorora mishonga yemakirini yakaratidza kuti kuwedzerwa kwemazuva ose kunogona kudzivirira zvirwere kubva pakudzoka kana kubva pane zvose zvinowanikwa kune vane ngozi yakawanda. Izvi zvinowedzera kuwedzerwa kuderedza chikamu cheruko hemoglobin inopararira, kudzivirira zvimwe zviitiko.

> Sources:

> National Heart, Lung, uye Blood Institute. Uchapupu hunotungamirirwa nehutachiona hweSirle Cell Disease: Report Panel Panel, 2014.

Kuisa Ropa Ndiro Kuwirirana Kurwara Mukurwara Kwemajeri Masero

Pane zvinhu zvakawanda zvinopinda muchisarudzo chekupa kuwedzerwa kweropa uye urongwa urwu haruna kufukidza zviratidzo zvose. Kuwedzerwa ropa hakusi kushandiswa kurapa chirwere chinokonzera ropa chinowanikwa muCSD sezvo zvinowanzoremeswa. Hydroxyurea, mushonga wemuromo, zviri nani zvakakosha kuderedza kucherechesa ropa. Sezvakaitwa nemishonga yose, zvinokosha kuti ukurukure njodzi uye zvakakosha zvekurapa nachiremba wako.