Kuchengetedza Antibodies Apo TSH Yakasikwa
Utachiona hwehutano hwekudzivirira hunoita nharo. Pane chimwe chinhu chaunogona kuita kudzivirira utachiona hwehutachiona, kana kuti huchengetedze kubva pakuipa? Kana iwe ukakumbira, vamwe magumo endocrinologist achakudzingai, kana kukuudzai kuti hamuna nzira dzokurapa. Kutsvakurudza kwekutsvaga, zvisinei, kutsigira kunzwisisa kuti Hashimoto's thyroiditis-chirwere chinogadzirisa muviri chinokonzera hypothyroidism-inogona kunge ichidzivirirwa, chinonoka, kana kuti chakamira zvachose isati yasvika pakuparadzwa kwehutano hwako hwetroroid uye kuwanda kwetachiona .
Muhurukuro pamusangano weWendocrine Society's Endo 2005, Dr. Ting Chang nevamwe vake vakataura pamusoro pekupa utachiona hwemishonga yemishonga yevhisi levothyroxine (zvinowanzozivikanwa mazita anosanganisira Synthroid, Levoxyl, uye Tirosint) kune Hashimoto's thyroiditis varwere. Vatendi ava vane chirwere chetachiona chinokurudzira hormone (TSH ), uye yakasarudzwa se "euthyroid," zvinoreva kuti maTSH awo aive akaenzana.Varwere ava, kunyange zvakadaro, vakanga vawedzera utachiona hweperoxidase (TPO) ma antibodies. chinoratidza huimoto yeHashimoto's thyroiditis.
Hafu yevarwere yakapiwa levothyroxine kwemwedzi mitanhatu uye imwe hafu haina kugamuchira kurapwa kwemishonga. Utachiona hwekuita maitiro uye autoantibody titers dzakayerwa mushure memwedzi mitanhatu. Zviwanikwa zvaikosha:
- Vaya vaigamuchira levothyroxine vainge vakaderera zvakanyanya nemaantiantibody mazinga , uye mazinga eanoripolisi akawedzera mune vamwe pakati peboka risingatendi.
- TSH miviri yakaderera muboka rakarapwa, rinosvika 0.5 vs 2.5 muboka risingatendi.
Vatsvakurudzi vakagumisa kuti early prophylactic (preventionative) levothyroxine mushonga inogona kubatsira kubatsira kuderedza kufambira mberi kwehupenyu hweHashimoto's thyroiditis.
Ichi hachisi chidzidzo chekutanga kuratidza kuti kurapwa kwekudzivirira kunogona kudzivisa kufambira mberi kweHashimoto kana kukurudzirwa kwepamusoro pee hypothyroidism.
Mumagazini yaMarch 2001, yakabudiswa neTroroid , vatsvakurudzi veGermany vakataura nezvekudzidza kwavo nezvevarwere vane euthyroid yeHashimoto, hafu yevaya vaibatwa ne levothyroxine kwegore, imwe hafu isingateereri. Mushure megore rimwe, ma-antibody mazinga uye lymphocytes, izvo zvinoratidza kuvhiringidza, zvakaderera zvikuru muboka rinogamuchira mishonga. Pakati peboka risina kutenderwa, maitiro e-antibody akasimuka kana akaramba akafanana.
Vatsvakurudzi vakagumisa kuti kudzivirira kurapwa kwevashandi veEuthyroid varwere vaHashimoto vakagadzirisa zviratidzo zvakasiyana- siyana zvehutachiona hweo autoimmune thyroiditis . Vakatofungawo kuti kurapa kwakadaro kunogona kukwanisa kufambira mberi kwechirwere cheHashimoto, kana kuti zvichidzivirira kukura kwe hypothyroidism.
Mune imwe dzidzo, vatsvakurudzi veJapan vakawana kuti kurapwa ne levothyroxine kunogona kuderedza chiitiko cheHashimoto's thyroiditis, pamwe nekubatsira kuderedza zviratidzo zvechirwere.
Muchidzidzo chevarwere vane chirwere cheHutmic Hashimoto, boka rimwe revarwere rakagamuchira levothyroxine kurapwa, uye rimwe boka harina kugamuchira kurapwa. Mushure memwedzi gumi nemashanu, boka rakarapwa rakanyanya kuwedzera mahwindo eT4, zvakaderera zvakanyanya TSH mazinga, uye kuderedza muviri we anti-thyroglobulin antibody (Tg-Ab) uye anti-thyroid peroxidase antibody levels.
Ukuru hwezvirwere zvetachiona zvakadererawo muboka rakarapwa, asi avo vasingagamuchiri kurapwa vaine kuwedzera kwehutori hwehutachiona , chiratidzo chekuputira gland.
Vatsvakurudzi vakatsanangura kuti kunyange levothyroxine kurapwa "inobvumirwa mu hypothyroid autoimmune thyroiditis varwere , kurapwa kunoratidzirwa kuvhara mararamiro ezvimhuka muhutano hwemhuka ichiri kukakavhirwa muhutachiona hweHashimoto's euthyroid apo chirwere chacho hachina kuparadza utachiona hutano hwakakwana hunoita kuti hypothyroidism. "
Vakatora, zvisinei, kuti hovothyroxine kurapwa pamisero yakachengetedza TSH panzvimbo dzakasara-yakaratidzika inoita kunge inoshanda kwete chete pakuderedza mazinga eanorantibody asiwo muhukuru hwegorosi, izvo zvingazopedzisira zvichidzivirira kufambira mberi kusvika pakuwedzera autoimmune hypothyroidism.
Shoko kubva
Sezvaunogona kuona, pane chiitiko chakanyanya chekutsvakurudza chinoratidza kuti kurapwa kwekuvharapa nevothyroxine kunogona kugadziriswa kune vanhu vane chirwere cheEuthyroid Hashimoto, vane maitiro akasiyana echirongwa cheTSH asi maitiro avo anorupikisi anoratidza uchapupu hwehutachiona hweHashimoto . Kurapa kwakadaro kunogona kuitika mune dzimwe nguva kubvisa hypothyroidism zviratidzo, kunonoka kuderedza kukwirira kwezvirwere zvehutachiona , kubatsira kudzivirira kuipa kwezvirwere zvemoto , uye kudzivirira kufambiswa kwe hypothyroidism.
Kana iwe uine zviratidzo zvehutano , chiitiko che " TV " chimiro, asi hauna kuongororwa nehutachiona hwemakemikari, unomiririra kuve nekuedzwa kwe TPO kuitwa nemushandi wako.
Kana iwe uine zviratidzo zvehutano, "TV" yakawanda, uye yepamusoro yezvirwere zvehutano, funga kubvunza kurapwa, uye kana chiremba wako asingadi, funga kutsvaga chiremba ane ruzivo kana akazaruka .
Sources
En-Ting Chang, Du-An Wu, Dee Pei, Shi-Wen Kuo, Ming-Chen Hsieh. [P2-552] Simba reL-Thyroxine Administration muVirwere neEuthyroid Hashimoto's Thyroiditis. Endocrine Society Endo 2005 Zvinyorwa
Thyroid, 2001 Mar; 11 (3): 249-55, "One-year prophylactic treatment of euthyroid Hashimoto's thyroiditis varwere vane levothyroxine: kune rubatsiro here?"
Duygu Yazgan Aksoy, et. al. "Migumisiro yeProphylactic Thyroid Hormone Kudzokorora muEuthyroid Hashimoto's Thyroiditis" Endocr J (Japan) Vol. 52: 337-343, (2005).