Hashimoto's thyroiditis ndiyo chirwere chetroimimune iyo inonzi autoimmune chirwere chinonzi, muUnited States, chinokonzera kupfuura chikonzero che hypothyroidism, utachiona husingaiti.
Chimwe chinhu chisingawanzobatanidzwa neHashimoto's thyroiditis ndiHashimoto's encephalopathy (akafuridzirwa se HE). Hashimoto's encephalopathy inorwara neuroendocrine iyo nzira dzisinganzwisisiki navanachiremba nevatsvakurudzi.
Zvinofungidzirwa kuti sehosha yaHashimoto, Hashimoto's encephalopathy inotarisana nemhando yezvisikwa, uye inokonzerwa nehurumende ine utsinye asi inokanganisa iyo inotarisa nhengo dzomuviri, nhengo dzemuviri uye matukisi. Mune mhaka yeHashimoto's encephalopathy chinangwa ndechoropi.
Cherechedza: Nokuti havasi varwere vose vane uchapupu hwehutachiwana hweHashimoto, dzimwe nyanzvi dziri kuratidza kuti mamiriro acho akafanirwa kutumidzwa kubvisa chibatanisi chaHashimoto, uye panzvimbo iyo anonzi " steroid-responsive encephalopathy inobatanidza ne autoimmune thyroiditis ."
Isu tinoziva kuti muHashimoto's encephalopathy, mazinga akawanda e antithyroid antibodies (utachiona peroxidase antibodies, kana TPO) inoratidzika kunge yakabatana nekuputika muuropi iyo inokwanisa kuratidzika mune zviratidzo zvakasiyana-siyana zvinoparadza.
Kakawanda Hashimoto's Encephalopathy Inoitika Sei?
Hashimoto's encephalopathy inoratidzika isingawanzoiti (kune vane gumi vanoverengeka vanorwara varwere vari muUnited States) asi zvinogona kunge kune vamwe vakawanda vanorwara vasingazivikanwi vasingazivi kana kuti vasingazivi.
Nemhaka yokuti haisi kuzivikanwa uye zviratidzo zvayo zvinonyanya kuongororwa neurological, zviri nyore kusaziva kana kusaona uye zviratidzo zveHashimoto zve encephalopathy zvinowanzokonzera kukanganisa kwehutano hwehutano.
Ivhareji yemakore ekutanga kweHashimoto's encephalopathy yakapoteredza makore 47. Izhinji huwandu hweHAR varwere vakadzi.
Anokwanisawo kuratidzira mukuyaruka kana zvichikwanisika kuregererwa. Zviratidzo zvevechiri kuyaruka zvinosanganisira kugunun'una, kuvhiringidzika, nekufungidzira. Dhesi pachikoro chinoshanda zvakare chiratidzo chinowanzoonekwa, pamwe chete nekupfuurira kunetseka kwekunzwisisa. Thyroid antibody mazinga inofanira kuongororwa kune chero yevechiri kuyaruka ane zviratidzo izvi, kunyange kana mamwe maitiro ehutachiona ari ejairika.
Zvimwe zviratidzo zvinowanzoonekwa nevanhu vakuru vane Hashimoto's encephalopathy zvinosanganisira zvinotevera:
- kuora mwoyo
- psychosis nekunyengera
- kudengenyeka
- matambudziko uye kuyeuka
- kupisa uye kumira mumisumbu inozivikanwa se myoclonus
- kusava nekubatana kwenyama
- headaches
- kuora mitezo
- matambudziko ekutaura
- unhu hunoshanduka.
- utsinye.
- unzenza.
- matambudziko uye kuyeuka.
- seizures
- kurara kusagadzikana
Anowanzofambira mberi nenzira mbiri: kana sekurwadza, kurwisa-kufanana nekurwisa kana kubatwa; kana kuti kuburikidza nekufambidzana kunofambira mberi mukuita demoa, kana kunyange coma. Dzimwe nguva, varwere vanonyatsoonekwa kuti vane chirwere, chirwere cheCreutzfeldt-Jakob, chirwere chepfungwa, kana chirwere cheAlzheimer.
Parizvino, hakusi kuongororwa kweHashimoto's encephalopathy. Kunyange zvazvo utachiona hwemakemikari hungave hwakareba, hunogona kunge husipo.
Saizvozvowo, mazinga eTSH anogona kunge ane hanya kana kuti angave akaenzana. Kurapa nehroid hormone replacement mishonga haigadzirise HE.
ANONYIRWA akabatwa nekutonga kunze kwezvimwe zvinokonzera zviratidzo.
Kurapa kwaHashimoto's Encephalopathy
Iko kunyanya kurapwa kweHashimoto's encephalopathy is oral corticosteroid mishonga, yakafanana ne prednisone. Varwere vakawanda vanoita zvinoshamisa mukurapa kwezvinodhaka, nevhareji yakakura kurapwa kwemavhiki mana kusvika matanhatu. Kufanana nematambudziko akawanda ekudzivirira, HE haaoneki kuti inoporesa, asi kunoporesa. Mushure mokurapa kwokutanga, chirwere ichi chinowanzosvika mukuregererwa.
Vamwe varwere vanogona kurega kurapwa kwemishonga kwemazana emakore, kunyange kune dambudziko rekudzokerazve mune ramangwana.
Kuwedzera kune steroid therapy, mamwe marapirwo akadai sokuti intravenous immunoglobulin uye kushandiswa kweplasma inoonekwa sarudzo.
Kunyange zvazvo isingadikanwi, Hashimoto's encephalopathy inogona kukonzera kushungurudzika, kusagadzikana kwenguva duku, kana kunyanya kuzvidya mwoyo. Izvo hazvisi kusvikira mamiriro acho ezvinhu aine maitiro akaoma, kana asingagamuchiri zviratidzo zveuropiyasiychiatric, kuti vanachiremba vakawanda vanotarisa zvinetso zvehutachiona, maronda, kana kuti nhoroondo yemhuri yehutachiona hwehutachiona.
Varwere vanowanikwa Hashimoto's encephalopathy vanotarisana nedambudziko rekuongorora uye zvirwere zvinogona kukanganisa. Nenzira yakanaka, vanhu vazhinji vanopindura mushonga unowanikwa nyore nyore. Kana iwe uchitambura zviratidzo zvakaoma zveuropognitive chiremba wako haakwanise kutsanangura, iva nechokwadi chekutaura nhoroondo yako yega kana yemhuri yeHashimoto's thyroiditis kana zvimwe zvirwere zvehutano.
> Sources:
> Carbone A, et. al. "Hashimoto's encephalopathy (HE): inonzi underimmune-mediated encephalopathy." Endocrine. 2016 Nov; 54 (2): 572-573.
> Kaczmarczyk A, et al. "Hashimoto's encephalopathy - isingaoneki encephalopathy nemashoko akanaka." Wiad Lek. 2016; 69 (6): 768-772.
> Laurent C et al. "Steroid-responsive encephalopathy inobatanidza ne autoimmune thyroiditis (SREAT): Maitiro, kurapwa uye mugumisiro mumatambudziko 251 kubva mumabhuku." Autoimmun Rev. 2016 Dec; 15 (12): 1129-1133. doi: 10.1016 / j.autrev.2016.09.008. Epub 2016 Sep 15.
> Litmeier S, et al. "Initial serum thyroid peroxidase antibodies nemigumisiro yakareba muSREAT." Acta Neurol Scand. 2016 Dec; 134 (6): 452-457. doi: 10.1111 / ane.12556.
PMID: 26757046