Melatonin uye Kuti Inogona Sei Kubatsira Kurara uye Kugadzirisa Matambudziko muAlzheimer's
Chirwere cheAlzheimer chirwere chinoparadza, asi marapirwo akasiyana-siyana akaita sehomoni melatonin inogona kukwanisa kuwedzera zviratidzo zvakaoma zvakadai sokushaya hope uye kupera zuva.
Alzheimer's uye Melatonin
Melatonin ine mabasa mazhinji mumuviri, asi inonyanya kukosha mukuraira kwekurara. Melatonin inobudiswa muuropi nehaini yepineal. Iyi gland inoburitsa nhamba yepamusoro ye melatonin panguva yemasikati, uye hormone inoratidzika kuva yakabatanidzwa mukudengenyeka kwekuchinja kwatinonzi takarara.
Kutsvakurudza kwenguva refu kwakagadzirisa kuti mazinga e-melatonin anowanzopera nezera, asi vanhu vane chirwere cheAlzheimer vane kunyanya kuderera-dzimwe nguva hafu yevanhu vakawanda vezera rimwe chete vasina chirwere. Uyewo, kuvhiringidza kurara kazhinji chiratidzo cheAlzheimer's. Mumakore achangobva kupfuura, zvidzidzo zvakawanda zvakaratidza kubatsira kwekuwedzera maratonin, kwete chete kuderedza zvinetso zvekurara zveAlzheimer, asi yekudzivirira zuva zvakare.
Kusvetwa kunoreva kunetseka kwetsika kunowanzojairika muhosha yeAlzheimer uye kunowanzoitika manheru. Pamusana pezvikonzero zvisiri pachena, vanhu vazhinji vane zviratidzo zveAlzheimer vakawedzera kuvhiringidzika , kuzvidya mwoyo , kushungurudzika uye kunyange kurwisana pakupera kwezuva. Maererano neAlzheimer's Association, inenge chikamu chechishanu chevanhu vane chirwere cheAlzheimer chichaona nguva yekupedza zuva, kazhinji mukati mezvikamu zvepakati chechirwere.
Sundowning inobhadhara kune avo vane Alzheimer uye inobatsira zvikuru kuchengetedza kunetseka uye kuneta. Nenzira, kune uchapupu hunoratidza kuti melatonin inogona kubatsira pakunyura kwezuva uye kukanganiswa kwekurara kwakabatana.
Zvimwe Zvipo zveMelatonin muAlzheimer's
Melatonin inogonawo kuva nezvimwe zvinobatsira. Icho chinopesana ne-antioxidant, chinoshanda kurwisa zvinokuvadza zvemakemikari zvinogona kukanganisa masero.
Zvinoratidzika kuva nehutachiona hwehutachiona hwehunoti, hunoreva kuti hunobatsira kudzivirira masero neuropi masero kubva mukukuvara. Pane humwewo uchapupu hwokuti kuva nekushaya kukwana kwe melatonin kunobatsira pakuora mwoyo.
Zvimwe zvidzidzo zvinoratidza kuti hormone inogona kuvandudza kuora mwoyo kwakagadzikana, kunyange zvazvo vatsvakurudzi vanosimbisa kuti migumisiro yakakwana uye kuti melatonin haisi "mushonga" wehosha yeAlzheimer yazara. Vamwe vatsvakurudzi vanonyevera kuti kukanganiswa kwehomoni kunenge kusinganzwisisiki munguva yekupedzisira-yeAlzheimer's .
Vatsvakurudzi vakatanga kutanga "melatoninergic" kana kuti mishonga ye-melatonin iyo yakareba-kuita uye ine zvinangwa zvakanyanya. Semuenzaniso, Rozerem (ramelteon) akakunda FDA kuvimbiswa kwekutora nguva refu kwekuvhiringidzika kwehope. Asi kusvika ikozvino, hapana mishonga ye-melatonin yakagadzirwa zvakananga kune chirwere cheAlzheimer kana sundowning.
Pasi Pasi
Zvimwe zvidzidzo zvezesayenzi zvinofanira kuitwa kuburikidza kushandisa melatonin supplementation muhosha yeAlzheimer kuti inzwisise zvakanakira kubatsirwa kwayo (kana kwete).
Asi kubvira apo melatonin inorondedzerwa sechiwedzera, inowanikwa pasina mushonga. Izvozvo zvichiti, usati wapa hormone kune mumwe munhu ane Alzheimer, unofanirwa kubvunza chiremba wake, uyo achakwanisa kuziva kana zvine musoro.
Sources:
Alzheimer's Association. "Kurara Nenyaya uye Kuderedza Sundowning
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ZVINOKUDZIDZA: Mashoko ari panzvimbo ino ndeongangwa dzekudzidzisa chete. Icho hachifaniri kushandiswa sechinzvimbo chekuchengetedza iwe pachako nechiremba ane chiremba. Ndapota ona chiremba wako kuti aongororwe uye kurapwa chero kupi zvako pamusoro pezviratidzo kana chirwere chechiremba .