Zvitsva zveMediterranean FDA-inogamuchirwa mishonga yekurapa
Neurology inokurumidza kushandura munda, uye hutsva hunoitika nguva dzose. Mumunda wechipfupa, mishonga mishanu mishonga inopesana nemaperembudzi yakagamuchirwa neChadya neDrug Administration (FDA) mumakore mashanu pakati pe2012 ne2017.
Zvinoshandiswa neMishonga Iyi
Yakawanda yemishonga iyi yakagamuchirwa kuti irege kukanganisa, iyo ndiyo inotanga kuitika pane imwe nzvimbo yeuropi panzvimbo pezvose panguva imwe chete.
Mukuwedzera, mamwe emishonga mitsva inopesana nekutengesa inoshandiswa mukuoma-kubata-kutapudza vana, sezvakaita Lennox-Gastaut syndrome.
Mimwe yemishonga iyi inoshandiswa kure-nereki zvakare, zvinoreva kuti vanachiremba vari kuzvitsanangurira zvimwe zvinhu kunze kwezvakaitwa neDFA kuti kambani iparidze.
Trokendi XR (Topiramate)
Kunyange zvazvo topiramate (Topamax) yakagamuchirwa neDFA muna 1997 kuitira kurapwa kwemaitiro okutanga okutanga, iyi ndiyo yakasunungurwa yakasunungurwa, yakagamuchirwa neDFA muna 2013. Trokendi XR inogona kushandiswa yoga kune varwere vane makore 10 kana kupfuura vanoona rusarura kana tonic-clonic kugumburwa uye sechipiri kurapwa kune varwere vane makore matanhatu kana kupfuura avo vane tsvina kana toniic-clonic kugumburwa kana Lennox-Gastaut syndrome.
Zvinokanganisa zvinogona kusanganisira kuvhiringidzika, zvinetso zvemanzwiro, dutu, kuneta, kunetseka kana kupisa kunzwa mukati meganda, zvinetso zvepfungwa, kuoma kuisa pfungwa, fivha, utachiona, anorexia, kuora kurasikirwa, kurara, kutya, zvinetso zvekuziva, uye kutapudza pfungwa nemafambiro.
Trokendi XR is capsule inotorwa kamwe kamwe pazuva.
Briviact (Brivaracetam)
Yakagamuchirwa muna 2016, brivaracetam inonyatsorongedzerwa sechipiri kurapwa kunobata zvishoma zvishoma zvishoma zvakagadziriswa zvinowanika muhutura mune varwere vane makore 16 kana kupfuura. Inoshanda nekubatanidza puroteni inonzi syaptic vesicle 2A, iyo inobatsira kumisa kugumburwa.
Migumisiro inogona kusanganisira kunyorera kana kurutsa, kuneta, dutu, uye kurara. Mhirizhonga inogona kutarisirwa sepiritsi, jekisi, kana mhinduro yemuromo, zvose zvinotorwa kaviri pazuva.
Qudexy XR (Topiramate)
Kufanana neTrokendi XR, Qudexy XR imwezve yakasunungurwa shanduro ye topiramate yakagamuchirwa mugore ra2014. Qudexy XR inoshandiswawo kugadzirisa mishonga yevarwere vane makore 10 kana kupfuura avo vane zvishoma kana kuti tonic-clonic kugumburwa, asi inogona kushandiswa sechipiri kune varwere vane makore maviri nevanopfuura vane hutachiwana kana kuti tonic-clonic kugumburwa kana Lennox-Gastaut syndrome zvakare. Trokendi XR inogumira kuvarwere vane makore matanhatu nekure.
Zvimwe zvinokonzerwa neKudexy XR zvinogona kusanganisira kuvhiringidzika, fivha, dutu, kurara, zvinetso zvepamusoro, kuoma kuisa pfungwa, anorexia, utachiona, matambudziko emanzwiro, kutya, kuora muviri, njere dzekufunga, kutsvaira kana kunetseka mukati meganda, uye kuderedza pfungwa nemafambiro . Zvinotorwa se capsule kamwe pazuva.
Aptiom (Eslicarbazepine Acetate)
Aptiom, yakagamuchirwa muna 2013, inoputika-gated sodium channel blocker inoshandiswa sechipiri kurapwa kune varwere vane kukanganisa kwemazuva ose. Nzira iyo inoshanda isiri pachena uye haisati yazivikanwa kana yakachengeteka kushandiswa kune vana vasati vava nemakore mana.
Migumisiro inogona kunosanganisira misoro, kusuruvara, kurara, kuneta, vertigo, kudengenyeka, kusvibiswa, kushushikana, kurwisana, chiratidzo chakaviri, dutu, uye kusagadzikana. Aptiom iplate inotorwa kamwe chete pazuva.
Fycompa (Perampanel)
Kungofanana nedzimwe zvirwere zvinopesana nemaperembudzi zvisati zvaitika, perampanel ine nzira itsva yekuita, inotarisa α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) ionotropic glutamate receptor. Perampanel inogona kuwirirana nemishonga yakafanana ne carbamazepine, oxcarbazepine, kana phenytoin uye inoshandiswa kurapa vanhu vakuru nevana vane makore gumi nemaviri kana kupfuura nekudzivirira zvishoma, kechipiri kukanganisa, kana kuti inowanzoita tonic-clonic kugumburwa .
Migumisiro inogona kunosanganisira kuora, kuora, kuwana, kunetseka, kuwira, kuenzanisa matambudziko, kurara, kusagadzikana, uye kushungurudzika. Fycompa ipiritsi inotorwa kamwe chete pazuva.
Mishonga Mitsva Inofanirwa Izvo Zvitsva Tariro
Parizvino, inenge chikamu chetatu chevarwere vane chirwere chekufa chinokonzera kusagadzikana zvakanaka nemishonga chete. Nokugadzira mishonga mitsva nemaitiro matsva, tarisiro yedu ndeyezuva rimwechete ine nyika iri kutora rusununguko.
> Sources:
> Franco V, French JA, Perucca E. Zvinosangana muChipical Development yeNew Antiepileptic Zvinodhaka. Research Research . January 2016; 103: 95-104.
> Center Watch. FDA Inogamuchirwa Zvinodhaka zveNeurology. 2017.