Osteoarthritis Yakawedzerwa kune Zita rezviratidzo zveDuloxetine
Cymbalta iri kubuda senzira yekurapa marwadzo asingagoneki musculoskeletal, kusanganisira osteoarthritis uye kusingaperi kurwadziwa kwekusuruvara , sezvo FDA yaibvumidza iyo iyo inoshandiswa muna 2010. Cymbalta (duloxetine hydrochloride) inodhaka yemishoni inogadzirwa naLilly. Yakatanga kugamuchirwa neRWA muna 2004 nokuda kwekunyanya kuora mwoyo. Yakagamuchirwa kwemhando dzakasiyana-siyana dzehutano hwepfungwa, asi ikozvino inorayirwawo nekusingaperi musumuloskeletal kurwadziwa.
Iyo Cymbalta Inoshandisa Sei Osteoarthritis uye Pain
Cymbalta inorondedzerwa serotononin uye norepinephrine reuptake inhibitor (SNRI). Inoshanda kuburikidza nekuwedzera zvinhu zvakasikwa muuropi, serotonin, uye norepinephrine, iyo inofungidzirwa kuti inogadzirisa zvirwere zvinorwadza kuuropi.
Kugamuchirwa kweCymbalta nokuda kwehutachiona hwemusculoskeletal, kusanganisira osteoarthritis uye kurwadziwa kwepashure, kwakabva pamigumisiro ye-double-blind, placebo-controlled, randomised clinical trials-three studies for low back pain and two for osteoarthritis. Mhinduro yakaratidza kuti varwere vanotora Cymbalta vaiva nehukuru hwakanyanya kuderedza kudarika varwere vanotora placebo.
Dosage uye Mirayiridzo
Cymbalta inowanikwa nemurairo chete. Chirwere ichi chinowanikwa sechinonoka-kusunungurwa capsule mu20, 30, uye 60-milligram simba. Chiremba wako achapa chirongwa chakakodzera chemamiriro ako ezvinhu uye angatanga iwe pamuto wepamusoro uye owedzere mubairo.
Iva nechokwadi chekumedza chipsule yose pasina kupwanya, kuparadzanisa, kutsva, kana kuzarura capsule.
Tora tsamba yako yezvinyorwa zvakajeka maererano nemirayiridzo pamusoro pekuraira. Iwe unogona kutora Cymbalta kana kuti usina kudya. Kana iyo inokonzera kushungurudza mudumbu, tora nechingwa. Iva nechokwadi kuti haufaniri kumisa mishonga pakarepo kana usina kutanga uchitaura nezvekuregererwa nechiremba wako.
Kana iwe ukamira kamwe kamwe, unogona kuve nemigumisiro isingafadzi kana yakaipa.
Iko Cymbalta Isingakodzeri Kune Vamwe Vanhu Here?
Chiremba wako achasarudza kana Cymbalta yakakodzera kurapwa kwako. Iva nechokwadi chekuudza chiremba wako kana iwe unonzi unozivikanwa ne duloxetine, kana iwe ukatora thioridazine kana MAO inhibitor. Ipa chiremba wako runyorwa rwemishonga yose uye mavitamini ayo waunotora. Kurukurai nezvehupi hupi hupi hwehutano hwaunayo uyewo tsika dzakadai sedoro rekushandisa.
Lilly anonyevera kuti zvidzidzo zvemhuka zvinoratidza Cymbalta inogona kukonzera kukuvara kwekuberekwa, kunetseka kwevakadzi vane pamuviri. Vanokurudzira kuti vashandise pakushandiswa pakudzivirira vana. Tsvaga chiremba wako asi kazhinji inenge isina kurongedzwa mune dzimwe nguva.
Nharaunda Dzakabatana
Matambudziko anowanzowanzosanganisira kushungurudza, kuoma muromo, kuvimbiswa, kurara, kutuka, uye kuderera kwechido. Migwagwa isina kufanana inosanganisira kushambidzika, chirwere, chirwere chemudumbu, kuchinja kumigwagwa, urutu, kuora musoro, kuneta, kurwadziwa kwepfungwa, misumbu, kushanduka pakuita zvepabonde, kana kudengenyeka. Cymbalta inogona kukonzera dzimwe migumisiro, dzimwe dzingave dzakanyanya. Kana ukava nemigumisiro yakakomba iyo inoratidzika semamiriro ezvinhu ekukurumidzira, tsvaka rubatsiro rwekukurumidza.
Mazano Anokosha
Cymbalta ine nyevero yebhokisi nyevero sezvinowanzoonekwa pane zvinodhaka zvinodhaka.
Yakawedzerwa muna 2014. Maererano nekurondedzera ruzivo rweCymbalta inopiwa nemuiti:
" Manyevero: Kuzviuraya Mafungiro uye Maitiro
• Kuwedzera kwengozi yekuzviuraya nemafungiro mukati mevana, vechidiki, uye vechidiki vakuru vanotora zvinodhaka
• Kutarisa kuwedzera uye kubuda kwekufunga kuzviuraya nemafungiro "
Ramba uchiyeuka kuti izvi zvinoratidzika kubva pane zvidzidzo zvevarwere vane dambudziko guru rekuora mwoyo uye zvimwe zvirwere zvepfungwa panzvimbo pane avo vanozvishandisa kune osteoarthritis. Asi iwe, mhuri yako, nevanochengeta vanofanira kuve vakangwarira kukucherechedzai nokuda kwekushungurudzika, kusagadzikana, kusagadzikana kwekuchinja maitiro, uye kuzviuraya.
Dzokorora chero ipi zvayo kubva pakarepo kune waunopa utano hwehutano.
Nyevero yakawedzerwawo mugore ra2014 nokuda kwehutano hwehutano , kuwira uye syncope (kuneta). Iyi ndiyo apo ropa rako rinodonha paunobuda pamubhedha kana kunze kwechigaro. Ngozi yekuwa yakawanda kana iwe uri kutora mishonga inopesana nehuwandu kuwedzera kuCymbalta. Kana iwe uchitova pangozi yekuwa kubva pazera kana mamwe mamiriro ezvinhu, izvi zvingave zvakanyanya kuipa neCymbalta, kunyanya apo iwe unotanga kuitora.
Kubatana Kwezvinodhaka Kunobatana neKymbalta
Zvimwe zvinodhaka zvakatorwa neCymbalta zvinogona kuwedzera kana kuderedza kushanda kwemishonga. Zvinodhaka kuti uchenjerere zvikuru, izvo zvinogona kukonzera kusangana kwezvinodhaka, zvinosanganisira:
- Quinolones
- Antidepressants
- Antipsychotic mishonga
- Narcotic kurwa nemishonga
- Kurara mishonga
- Tranquilizers
Sources:
> Cymbalta. Kunyora Mashoko . Eri Lilly naCh http://pi.lilly.com/us/cymbalta-pi.pdf
> Duloxetine (Nemuromo), Micromedex Consumer Mishonga Information, PubMed Health, US National Library yemishonga. Dec. 1, 2017. https://www.ncbi.nlm.nih.gov/pubmedhealth/PMHT0010059/?report=details#uses.
> Physicians desk reference 2017 . Montvale, NJ: PDR, LLC; 2016.