Miti yakagadzirwa neMitambo uye Mafuta Anogadzira Zvipembenene Zvizhinji
Kusagadzikana kwezvinodhaka zvinokonzerwa nemishonga ndeyemireni-yekare yekugadzirira mishonga yemishonga yevarwere kunwa, kumedza, kuisa kana kushandiswa paganda. Iyo ndiyo inowanzosiyana-siyana yezvinodhaka zvinodhaka zvakaitwa nevashambadziri nevadzidzisi vezvemishonga mune zvemharaunda uye mapepa maharapital. Uye pasinei ne "nonsterile" mazita, kuita miitiro yakagadzirirwa maererano nemitemo yepamutemo uye yehutano kunoda kutevedzera mitemo yakasimba yekuchengetedza nekuchengetedza kushandiswa kwemishonga inoshandiswa mishonga yakachena uye potency; kuve nechokwadi chekusanganisa; kupa zvikafu zvakakodzera, kuchengetwa, uye kuiswa mazita; uye kuchengetedza nzvimbo dzose dzebasa uye zvishandiso zvakachena sezvinobvira.
Kusiyana kwakanyanya pakati pekusava nekugadzirisa uye kusina kukonzera kunokonzera kuti madhiragi anowanikwa sei. Mishonga yakagadzirirwa kuvhara, kuvharirwa kana kushandiswa kune ziso inofanira kuwedzerwa maererano nemitemo uye mitemo yekusakatika yakaoma nokuti mabhakitiriya kana fungidzi zviripo muzvikamu-per-trillion zvinogona kuisa upenyu hwevarwere pangozi. Kuchengetedza kusvibiswa kunokosha kana kuita zvisizvo zvisingaiti, asi zvinokonzera hazvifaniri kushanda munzvimbo dzakakwana dzisina kuchena dzakadai sekuchenesa.
Chii Chinogadzirwa Nokusaziva Chinhu Chichiwedzera?
Tsanangudzo yakazara yekusagadziriswa kusina kuwanikwa kwakaitwa newebsite yeWebizlet inotsanangura mutsika se "yekugadzirisa zvinogadziriswa, kusungurudza, mafuta nemafuta, powders, suppositories, capsules, uye mahwendefa." Ive tsanangudzo yakazara yakawanda inogona kutsanangura kusina kwekunokonzera kusina kuiswa mumasero akareruka, akaenzana uye akaoma.
Kurongeka kunoenderana nekugadzirisa kugadziriswa kwemufananidzo wekurapa ndeye, zvipingamupinyi izvo zvinogadzirwa nemurwere uye mutongi, uye kuti fomu yakapedzwa inofanira kutarisirwa nekuchengetwa sei.
Kusawirirana kwemaitiro asina kukodzera kunosanganisira kusanganiswa mishonga maererano nemaitiro akaumbwa, kana kuti "mapepa," uye kusika mvura shanduro yemishonga zvinowanzosengeswa chete semapiritsi kana makapisisi.
Vanachiremba navana veterinarian vanowanzokumbira marudzi aya emishonga kumucheche nemhuka dzisingakwanisi kumedza mapiritsi kana kuti dzinoda madhadzi maduku kudarika izvo zviri muzvigadzirwa zvebhizimisi.
Yepamutemo US Pharmacopeia maforomo anovapo nokuda kwema 125 maitiro asina kushandiswa. Mapoka anojekesa kuti ma APIs uye zvisingabatsiri zvinoshandiswa kushandiswa, uyewo nzira yekuyera uye kusanganisa zvinoshandiswa, kunyora mishonga yemishonga yakagadzirwa uye kutsanangura zuva rokupera, iyo, mune pharmacy chinoreva, ndiyo "nguva isingashandisi." Nhengo mbiri dzeSPP dzakasara dzisina kushandiswa kwezvinodhaka zvinonzi alprazolam kumiswa kwemashoko (semuenzaniso, mapiritsi eXanax kubva kuPfizer) uye generic standard-release-morphine sulfate suppositories.
Kugadziriswa kwemazuva mashoma kunosanganisira kuita mazamu ane mishonga inogona kukuvadza kana kugadzirira inoda kushandiswa kwakakosha. Fentanyl troche, iyo inonyatsozivikanwa seLollipops, uye mafuta anokwanisa kushandiswa chete nemagetsi anowira munharaunda iyi. Vanachiremba vanachiremba, oncologists, uye dermatologist vanowanzorayira mishonga inoda kuwandisa kusinganzwisisiki. Dhiyabhorosi data pamusoro pekugadzira maitiro uye mazuva ekupedzisira haasati abudiswa kune mazhinji aya.
Mashoma ma pharmacy anoita zvinorema zvisingagoni kushandiswa, izvo zvinoda kudzidziswa zvakanyanya uye zvigadzirwa zvakakosha kuita michina yakafanana nekubudiswa-capsules yakatambanudzwa uye kutenderera kwemashure.
Ndeapi Mitemo Iripo Nokusagadzikana Kuwedzera?
USP 795 "Pharmaceutical Compounding ---- Zvisizvo Zvisingagadziriswi" inoita kuti mitemo yemasimist uye magadzirirwo emishonga inofanira kutevera pavanenge vachigadzira mafomu akaenzaniswa nemafungiro anoreva kutorwa nemuromo, akaiswa pamagetsi kana kushandiswa pamusoro. Chitsauko chacho chakavandudzwa, chakawedzerwa uye chakabudiswa zvakare muna Chivabvu 2011 kuti kusimbise kukosha kwekunyora zvose zvinogadzirisa maitiro, kuisa mazita emishonga yakawandisa zvakajeka nema API uye kupfuura mamwe mazuva ekushandiswa, uye kushandisa mvura yakachena kwezvose zvinosanganiswa nekuchenesa zvine chokuita nekusanganiswa kwemaitiro.
Ikubatanidzwa mundima ino inopa tsanangudzo yakawanda pane izvo USP 795 inoda, asi zvinhu zviviri zvinounza kujekesa.
Chokutanga, shengo yeCommitteeing Compounding Committee Committee, Patricia Kienle, RPh, MPA, FASHP, akaudza Pharmacy Purchasing & Products , "Kunyange zvirongwa zvisiri nyore, zvakadai sokugadzirisa kushandiswa kwemishonga inorwisa mabhakitiriya, zvinoreva kuwirirana uye saizvozvo, zvakafukidzwa nechitsauko chino."
Chechipiri, USP 795 inotora simba remurairo. Zvigadziro zvaro zvinogona kunge zviri, uye zvinomanikidzirwa neU.S. Food and Drug Administration agents uye nehurumende yehurumende yevakuru vezvemishonga. Vose vehurumende vakatora USP 795 senheyo yekutanga yekuchengeteka uye yepamutemo isingagadziriswi, uye vamwe vakagadzira mamwe mitemo yezvikwata. Muchidimbu, kunamatira ku USP 795 mitemo inoshandisa vanachiremba uye nyanzvi pamakona akanaka ekutarisira utano uye mutemo.