Kutsvakurudza kwakaratidza kuti kurapwa neododacid iodine yekenza yakanyatsosiyaniswa nekenza yakabatana nehuwandu hwehutano hwemhando mbiri dzekenza yeropa: yakaoma myeloid leukemia uye isingaperi myeloid leukemia.
"Kusiyanisa" chirwere chetachiona chinoreva maitiro uye mufambiro wemasero ekenza, uye mune kenza yakasiyana yakasiyana-siyana yekenza, masero anotarisa uye anoita semasero echitachiona anowanzoitika.
Zvakanyatsosiyanisa utachiona hwetachiona hunosanganisira mapirasi epilestry. carcinoma, follicular thyroid carcinoma, uye Hürthle cell carcinoma (HCC).
Iodine inodhaka yakawandisa inowanzoitwa sechikamu chekurapa kwekenza yekenza , kazhinji mushure mekuvhiyiwa kubvisa gorosi gland. Iodine inonzi radioactive, inozivikanwawo seRI, inopiwa kubatsira kubvisa chero mishonga yehutori yakasara mushure mekuvhiyiwa, senzira yekudzivisa kudzoka kwekenza yekemikari inogona kuitika mukugara kwechirwere chetachiona.
Kunyange zvazvo kutsvakurudza kwave kuratidza kuti vakapona kanhiyo yekenza vakawana RAI vanotarisana nehuwandu hwehutachiwana huwandu hwemakondomu echipiri , iyi ndiyo nguva yokutanga iyo yakakosha uye yakaratidza ukama yakawanikwa pakati peyodine ye-radioactive yekenza yekenza uye kuwedzera kwekuda kwezvose zviri zviviri uye isingaperi myeloid leukemia.
NezveMyeloid Leukemias
Chirwere chinonzi myeloid leukemia (AML), chinozivikanwa sechirwere chemyelogenous leukemia, inoratidziro yekenza yeropa inofambira nokukurumidza uye inogona kuuraya kana isingarapwa.
AML inogona kupararira kune dzimwe nhengo dzomuviri kusanganisira lymph nodes, chiropa, spleen, uropi, mutsara, uye testicles. IAmerican Cancer Society inofungidzira kuti kuchave nezviitiko zvinopfuura 21,000 zvitsva zve AML muna 2017, uye vanenge 10 600 vakafa kubva AML. AML inowanikwa vasati vava nemakore makumi maviri nemashanu, uye muvhareji wezera reAAML 67.
Makore mashanu ehupenyu hwehupenyu hwe AML ndeye 26 muzana.
Kurwara myeloid yeukemia (CML), iyo inozivikanwawo seisingagumi myelogenous leukemia, inogara isingagumi chekenza yeropa. IAmerican Cancer Society inofungidzira kuti inenge 9 000 mitsva itsva ye CML ichaonekwa muna 2017, ine vanhu vanoda kusvika 1110 vakafa. Ivhareji yemakore ekuongororwa ndeye 64. Makore mashanu ehupenyu hwehupenyu hwe CML inenge inenge 75 muzana.
Vatsvakurudzi vakacherechedza boka revakadzidza revarwere vakanyatsosiyanisa kanzera yekodhi kuitira kuti vaverengere njodzi dzechipiri chekenza yeropa. Muchidzidzo, varwere vanosvika 148.215 vane chirwere chetachiona chakasiyana-siyana vakaongororwa. Kune chikamu chezana makumi mashanu kubva kune makumi mashanu evarwere, kurapwa kwavo chete kwaiva utachiona hwehutachiona, chirwere chokubvisa utachiona hweganda. Zvose zvinokwana 47 muzana zvine utachiona hwehutachiona, pamwe neyodine yakasara yakasara yekurapa.
Pakati peboka revarwere vakadzidza, varwere vanokwana 783 vakagadzira kenza yechipiri yeropa pamusoro penguva yekudzidza yakapedza makore 6.5.
Kuenzaniswa nevarwere vaingova ne-thyroidectomy chete, varwere avo vaiva nerayodine ye-radioactive vakawedzera kukurumidza kutarisana nekunetseka kwekukurumidza kuva myeloid leukemia kana kusingaperi myeloid leukemia.
Dambudziko racho rakanga rakafanana kana murwere aiva nechirwere chepasi, chakasviba kana chepamusoro.
Pakati pevaya vakapona nekenza yehutano yakagadzira AML, kuponeswa kwemashoko kwemakore 1.2 kwaivewo kwakanyanya kudarika mumiriri wemakore 2.9 muvanhu vasina kumbove nehutachiona hwehuyodini.
Shoko Rinobva
Iyi tsvakurudzo inoratidza kuti varwere vakanyatsosiyanisa kanhi yekenza yakadai sepilillary, follicular, kana chirwere chemusero cheHurthle, uye vanogamuchira i-radioactive iodine yakasara kubhadhara kurapa, vakawedzera mungozi yekutanga yekukura myeloid leukemia uye isingaperi myeloid leukemia. Chirwere chinokonzera chirwere chinokonzera mutezo chinowedzerawo kuora mwoyo kwevarwere mushure mehutachiona hwehutachiona hwehuyodine.
Vatsvakurudzi vanokurudzira kuti chete varwere vane hutano hwepamusoro hwehutano hunoitwa hutachiona hune iodine ye-radioactive yepamusoro yakasiyana-siyana yekenza yekenza.
Kana iwe uine chirwere chetachiona chakasiyana-siyana uye chiremba wako anokurudzira kuti iodine irapwe mushonga, funga kuwana imwe pfungwa kubva kune imwe nyanzvi.
Kana uine iodine ye-radioactive munguva yakapfuura, kana kuti uve nayo mune ramangwana, iva nechokwadi chokuti nguva nenguva kuongororwa uye kuongororwa kweaikenza ropa iri chikamu chehupenyu hwako huripo huripo. Iwe unogona kuongororwa nguva nenguva nekuongororwa kweropa, uyewo chromosomal uye maitiro ekuongorora.
Uyewo, ivai pane kutsvaga zviratidzo zvekukurumidza uye kusingaperi kwemyeloid leukemia, iyo inogona kusanganisira kuneta, kunzwa manheru, kunzwa kuderedzwa kushandisa muviri, zvirwere zvinowanzoitika, kushungurudzika nyore, fever, kurasikirwa kwechido, kupererwa kwemweya, kuora kwekurema, usiku kupika, chizungu, kubuda ropa, nguva dzose nosebleeds, mapurasitiki
> Kwakabva:
> Molenaar, Remco J. et al. "Ngozi yeHematologic Malignancies Mushure meRadioiodine Kuchengetedzwa Kwezvakasiyana-siyana neTroroid Cancer," Journal of Clinical Oncology, http://ascopubs.org/doi/abs/10.1200/JCO.2017.75.0232?journalCode=jco